Reactome | OTUB2 [nucleoplasm]

OTUB2 [nucleoplasm]

Stable Identifier

R-HSA-6783260

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Ubiquitin thioesterase OTUB2, OTUB2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96DC9 OTUB2

Gene Names

OTUB2, C14orf137, OTB2, OTU2

Chain

chain:1-234

Reference Genes

BioGPS Gene:78990 Q96DC92

COSMIC (genes):OTUB2 OTUB2

CTD Gene:78990 Q96DC92

dbSNP Gene:78990 Q96DC92

ENSEMBL:ENSG00000089723 OTUB2

HGNC:20351 Q96DC92

KEGG:hsa:78990 Q96DC92

Monarch:78990 Q96DC92

NCBI Gene:78990 Q96DC92

OMIM:608338 Q96DC92

UCSC:Q96DC9 Q96DC92

Reference Transcript

RefSeq:NM_023112.3 Q96DC92

Participates

as a candidate of

OTUB1,(OTUB2) [nucleoplasm] (Homo sapiens)

Other forms of this molecule

OTUB2 [cytosol]

Inferred To

OTUB2 [nucleoplasm] (Bos taurus)

OTUB2 [nucleoplasm] (Caenorhabditis elegans)

OTUB2 [nucleoplasm] (Canis familiaris)

OTUB2 [nucleoplasm] (Drosophila melanogaster)

OTUB2 [nucleoplasm] (Sus scrofa)

otub2 [nucleoplasm] (Xenopus tropicalis)

Otub2 [nucleoplasm] (Mus musculus)

Otub2 [nucleoplasm] (Rattus norvegicus)

Cross References

OpenTargets

ENSG00000089723

ENSEMBL

ENSG00000277276, ENSP00000451283, ENSP00000487491, ENST00000628711, ENSG00000089723, ENST00000553723, ENSP00000478628, ENST00000203664, ENSP00000203664, ENST00000617748

HPA

ENSG00000089723-OTUB2

GeneCards

OTUB2

PRO

Q96DC9

Pharos - Targets

Q96DC9

GlyGen

Q96DC9

PDB

8CMS, 5QIT, 5QIS, 5QIZ, 5QIY, 5QIX, 5QIW, 5QIQ, 5QIR, 4FJV, 5QIU, 5QIV, 1TFF, 5QIP, 5QIO

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UHC7 MKRN1	2	p-S109-MKRN1 [cytosol] (R-HSA-8948758) MKRN1 [cytosol] (R-HSA-976042)	0.556	3
UniProt:Q9Y4K3 TRAF6	8	TRAF6 [cytosol] (R-HSA-166366) K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) TRAF6 [plasma membrane] (R-HSA-936955) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227) TRAF6 [endosome membrane] (R-HSA-450272) PolyUb-TRAF6 [cytosol] (R-HSA-6782845) K48polyUb-TRAF6 [cytosol] (R-HSA-6783233)	0.556	3
UniProt:Q8IUQ4 SIAH1	1	SIAH1 [cytosol] (R-HSA-374563)	0.556	3
UniProt:P54252 ATXN3	2	ATXN3 [nucleoplasm] (R-HSA-6783285) ATXN3 [cytosol] (R-HSA-5625607)	0.556	9

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