HSPG binds LPL dimer

Stable Identifier
R-HSA-6784861
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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LPL enzyme is catalytically active as a dimer composed of two glycosylated subunits of LPL connected in a head-to-tail arrangement by non-covalent interactions. It is synthesised in adipocytes and exported to the luminal side of the capillary endothelium where it binds heparan sulfate proteoglycan (HSPG), serving as an membrane anchor for the LPL dimer (Lookene et al. 1997, Berryman & Bensadoun 1995).

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