MonoUb-K561,p-T691,S717-FANCD2 [nucleoplasm]

Stable Identifier
R-HSA-6785318
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q9BXW9 FANCD2
Gene Names
FANCD2, FACD
Chain
chain:1-1451
Reference Genes
BioGPS Gene:2177 FANCD2
COSMIC (genes):FANCD2 FANCD2
CTD Gene:2177 FANCD2
dbSNP Gene:2177 FANCD2
ENSEMBL:ENSG00000144554 FANCD2
HGNC:3585 FANCD2
KEGG Gene (Homo sapiens):2177 FANCD2
Monarch:2177 FANCD2
NCBI Gene:2177 FANCD2
OMIM:613984 FANCD2
UCSC:Q9BXW9 FANCD2
Reference Transcript
Other Identifiers
0006770037
11732535_a_at
11736546_at
11736547_a_at
11736548_s_at
11756910_x_at
11761656_at
1568889_PM_at
1568889_at
1568891_3p_x_at
1568891_PM_x_at
1568891_x_at
16937505
17123142
2177
223545_PM_at
223545_at
242560_PM_at
242560_at
2610206
2610210
2610211
2610242
2610243
2610245
2610246
2610247
2610248
2610250
2610251
2610252
2610254
2610255
2610256
2610257
2610258
2610259
2610260
2610261
2610262
2610263
2610264
2610265
2610266
2610267
2610268
2610269
2610271
2610272
2610273
2610274
2610275
2610277
2610278
2610280
2610281
2610283
2610284
2610285
2610286
2610287
2610288
2610289
2610290
2610291
2610292
2610293
2610294
2610296
2610297
2610298
2610299
2610301
2610303
2610304
2610305
2610307
2610308
2610309
2610310
2610311
2610312
2610313
2610314
2610927
2610928
2610929
2610933
2610934
2610935
2610936
2610937
2610939
2610940
2610941
53423_i_at
53426_r_at
65277_at
8077731
87453_s_at
87455_at
A_23_P143994
A_23_P345678
A_32_P24165
GE83604
GO:0000003
GO:0000278
GO:0000785
GO:0000793
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0005829
GO:0006259
GO:0006281
GO:0006950
GO:0006974
GO:0007049
GO:0007059
GO:0007129
GO:0007165
GO:0007276
GO:0008150
GO:0009058
GO:0010332
GO:0016604
GO:0019899
GO:0030154
GO:0031573
GO:0032991
GO:0034599
GO:0034641
GO:0036297
GO:0043226
GO:0045589
GO:0048854
GO:0048856
GO:0050727
GO:0051090
GO:0051276
GO:0070182
GO:0097150
GO:1990391
GO:1990918
GO:2000348
HMNXSV003019165
HMNXSV003036583
Hs.278187.0.A1_3p_at
Hs2.423134.1.S1_3p_s_at
Hs2.423134.1.S1_3p_x_at
ILMN_1657634
ILMN_1712122
ILMN_1810703
ILMN_2235137
PH_hs_0023045
PH_hs_0041048
TC03000051.hg
g13183880_3p_at
Participates
as a component of
Other forms of this molecule
FANCD2 [nucleoplasm]
p-T691,S717-FANCD2 [nucleoplasm]
Inferred To
phospho-fancd2 [nucleoplasm] (Danio rerio)
phospho-fancd2 [nucleoplasm] (Xenopus tropicalis)
phospho-FANCD2 [nucleoplasm] (Bos taurus)
phospho-FANCD2 [nucleoplasm] (Canis familiaris)
phospho-FANCD2 [nucleoplasm] (Gallus gallus)
phospho-FANCD2 [nucleoplasm] (Sus scrofa)
phospho-Fancd2 [nucleoplasm] (Mus musculus)
phospho-Fancd2 [nucleoplasm] (Rattus norvegicus)
Modified Residues
Name
O-phospho-L-serine at 717
Coordinate
717
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 691
Coordinate
691
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
ubiquitinylated lysine at 561
Coordinate
561
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (12)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P51587 BRCA2  20 0.688 16
 UniProt:Q16658 FSCN1  1 0.649 6
 UniProt:P49959 MRE11  2 0.646 6
 UniProt:O60934 NBN  3 0.626 6
 UniProt:Q9HB96 FANCE  1 0.616 4
 UniProt:P49716 CEBPD  1 0.612 8
 UniProt:Q9NVI1 FANCI  3 0.589 2
 UniProt:P38398 BRCA1  20 0.583 3
 UniProt:Q92878 RAD50  1 0.578 4
 UniProt:P56180-2 TPTE      0.569 3
 UniProt:O00255 MEN1  4 0.524 4
 UniProt:Q14676 MDC1  6 0.483 2
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