NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC)

Stable Identifier
R-HSA-6785438
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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NSUN2 transfers methyl groups from S-adenosylmethionine to the 5 positions of cytidine-40, cytidine-48, cytidine-49, and cytidine-50 of tRNA(Gly)(GCC) (Auxilien et al. 2012, Khoddami and Cairns 2013).

Literature References
PubMed ID Title Journal Year
23604283 Identification of direct targets and modified bases of RNA cytosine methyltransferases

Khoddami, V, Cairns, BR

Nat. Biotechnol. 2013
22995836 The human tRNA m (5) C methyltransferase Misu is multisite-specific

Auxilien, S, Guérineau, V, Szweykowska-Kulińska, Z, Golinelli-Pimpaneau, B

RNA Biol 2012
Participants
Participant Of
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Catalyst Activity
Catalyst Activity
Title
tRNA (cytosine-5-)-methyltransferase activity of NSUN2 [nucleoplasm]
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