FANCM binds FAAP24

Stable Identifier
R-HSA-6785607
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

FANCM binds FAAP24, forming a complex that recognizes DNA interstrand crosslinks, thus triggering the Fanconi anemia repair pathway (Ciccia et al. 2007, Kim et al. 2008).

Literature References
PubMed ID Title Journal Year
17289582 Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM

Ciccia, A, Ling, C, Coulthard, R, Yan, Z, Xue, Y, Meetei, AR, Laghmani, el H, Joenje, H, McDonald, N, de Winter, JP, Wang, W, West, SC

Mol. Cell 2007
18174376 Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

Kim, JM, Kee, Y, Gurtan, A, D'Andrea, AD

Blood 2008
Participants
Participant Of
Orthologous Events
Authored
Reviewed