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What is Reactome ?
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TLR1 [plasma membrane]
Stable Identifier
R-HSA-6787702
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Toll-like receptor 1, TLR1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of Immune System (Homo sapiens)
Diseases associated with the TLR signaling cascade (Homo sapiens)
IRAK4 deficiency (TLR2/4) (Homo sapiens)
Defective IRAK4 does not bind MyD88:MAL:BTK:activated TLR2/4 (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
MyD88 deficiency (TLR2/4) (Homo sapiens)
Defective MyD88 does not bind MAL(TIRAP):TLR2/4 (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Defective MyD88 does not oligomerize within the activated TLR2/4 complex (Homo sapiens)
MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
TLR2:TLR1 binds SARS-CoV-2 E pentamer (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TLR2:TLR1:E:S3:M:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
ER-Phagosome pathway (Homo sapiens)
IKKB phosphorylates SNAP23 (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
Defensins (Homo sapiens)
Beta defensins (Homo sapiens)
Beta defensin 103 activates TLR1:TLR2 (Homo sapiens)
Beta defensin 103:TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Regulation of TLR by endogenous ligand (Homo sapiens)
SFTPA/SFTPD binds TLR2:TLR1 (Homo sapiens)
SFTPA/SFTPD:TLR2:TLR1 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
Activated TLR2/4 interacts with MAL (TIRAP) (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex (Homo sapiens)
IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP is phosphorylated by BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TRAF6 binds to hp- IRAK1 (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TRAF6 binds to p-IRAK2 (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TLR1:TLR2 is recruited to ligand:CD14 (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
Activated TLR2/4 interacts with MAL (TIRAP) (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex (Homo sapiens)
IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP is phosphorylated by BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TRAF6 binds to hp- IRAK1 (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TRAF6 binds to p-IRAK2 (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
Activated TLR2/4 interacts with MAL (TIRAP) (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex (Homo sapiens)
IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
MyD88 forms a complex with TIRAP:activated TLR2/4 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 (Homo sapiens)
MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TIRAP is phosphorylated by BTK (Homo sapiens)
TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TRAF6 binds to hp- IRAK1 (Homo sapiens)
TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
TRAF6 binds to p-IRAK2 (Homo sapiens)
TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] (Homo sapiens)
oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] (Homo sapiens)
activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] (Homo sapiens)
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane] (Homo sapiens)
TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] (Homo sapiens)
TLR1:TLR2 [plasma membrane] (Homo sapiens)
TLR1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15399 TLR1
Gene Names
TLR1, KIAA0012
Chain
signal peptide:1-24, chain:25-786
Reference Genes
BioGPS Gene:7096 TLR1
COSMIC (genes):TLR1 TLR1
CTD Gene:7096 TLR1
dbSNP Gene:7096 TLR1
ENSEMBL:ENSG00000174125 TLR1
HGNC:11847 TLR1
KEGG:hsa:7096 TLR1
Monarch:7096 TLR1
NCBI Gene:7096 TLR1
OMIM:601194 TLR1
UCSC:Q15399 TLR1
Reference Transcript
RefSeq:XM_011513742.4 TLR1
RefSeq:XM_024454196.2 TLR1
RefSeq:XM_017008572.3 TLR1
RefSeq:XM_005262662.6 TLR1
RefSeq:XM_011513743.2 TLR1
RefSeq:NM_003263.3 TLR1
RefSeq:XM_017008571.3 TLR1
RefSeq:XM_011513744.2 TLR1
RefSeq:XM_011513745.4 TLR1
Other Identifiers
11758377_s_at
16975213
210176_PM_at
210176_at
229968_PM_at
229968_at
2766205
2766206
2766207
2766209
2766211
2766212
2766214
2766216
2766218
2766220
2766221
2766222
2766223
2766224
2766225
2766226
2766227
2766228
2766229
2766230
2766231
2766232
2766233
2766234
2766235
2766237
2766239
2766240
2766241
2766242
36243_at
46491_at
7096
8099834
84241_at
A_23_P10873
A_32_P31123
A_32_P4934
D13637_at
GE56281
GE865365
GE879343
GO:0001774
GO:0002224
GO:0002376
GO:0004888
GO:0005515
GO:0005794
GO:0005886
GO:0006952
GO:0006954
GO:0006955
GO:0007165
GO:0008289
GO:0016020
GO:0016787
GO:0030670
GO:0031410
GO:0032493
GO:0032755
GO:0032757
GO:0032760
GO:0034137
GO:0035354
GO:0035663
GO:0038023
GO:0042116
GO:0042495
GO:0042802
GO:0043235
GO:0045087
GO:0045121
GO:0061809
GO:0071723
GO:0071727
GO:0098542
HMNXSV003022056
Hs.264347.0.A1_3p_at
ILMN_1654560
ILMN_1674789
ILMN_1731048
ILMN_1889841
PH_hs_0022291
TC04002916.hg
g4886482_3p_at
Participates
as a component of
TLR1:TLR2 [plasma membrane] (Homo sapiens)
Inferred To
TLR1 [plasma membrane]
(Canis familiaris)
TLR1 [plasma membrane]
(Sus scrofa)
tlr1 [plasma membrane]
(Danio rerio)
MstProx [plasma membrane]
(Drosophila melanogaster)
TLR1A [plasma membrane]
(Gallus gallus)
Toll-9 [plasma membrane]
(Drosophila melanogaster)
Homologues of TLR1 [plasma membrane]
(Drosophila melanogaster)
Homologues of TLR1 [plasma membrane]
(Gallus gallus)
Tlr1 [plasma membrane]
(Mus musculus)
Tlr1 [plasma membrane]
(Rattus norvegicus)
TLR1B [plasma membrane]
(Gallus gallus)
Toll-4 [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
XP_005262719.1
,
XP_016864061.1
,
XP_016864060.1
,
XP_011512045.1
,
XP_011512044.1
,
XP_011512046.1
,
NP_003254.2
,
XP_024309964.1
,
XP_011512047.1
Guide to Pharmacology - Targets
1751
OpenTargets
ENSG00000174125
ENSEMBL
ENSP00000354932
,
ENSP00000421259
,
ENST00000502213
,
ENST00000308979
,
ENSG00000174125
HPA
ENSG00000174125-TLR1
GeneCards
TLR1
PRO
Q15399
Pharos - Targets
Q15399
GlyGen
Q15399
PDB
7NUW
,
6NIH
,
7NUX
,
7NT7
,
2Z7X
,
1FYV
HMDB Protein
HMDBP12415
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BXR5 TLR10
1
TLR10 [plasma membrane]
(R-HSA-167926)
0.573
3
UniProt:O60603 TLR2
3
TLR2 [plasma membrane]
(R-HSA-167992)
TLR2 [secretory granule membrane]
(R-HSA-6804777)
TLR2 [plasma membrane]
(R-HSA-9637646)
0.508
3
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