Reactome | HAO2 [peroxisomal matrix]

HAO2 [peroxisomal matrix]

Stable Identifier

R-HSA-6787806

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

peroxisomal matrix

Synonyms

Hydroxyacid oxidase 2, HAOX2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NYQ3 HAO2

Gene Names

HAO2, HAOX2, GIG16

Chain

chain:1-351

Reference Genes

BioGPS Gene:51179 HAO2

COSMIC (genes):HAO2 HAO2

CTD Gene:51179 HAO2

dbSNP Gene:51179 HAO2

ENSEMBL:ENSG00000116882 HAO2

HGNC:4810 HAO2

KEGG:hsa:51179 HAO2

Monarch:51179 HAO2

NCBI Gene:51179 HAO2

OMIM:605176 HAO2

UCSC:Q9NYQ3 HAO2

Reference Transcript

Other Identifiers

11727665_a_at

11741521_a_at

16669347

220801_PM_s_at

220801_s_at

2354383

2354386

2354387

2354388

2354390

2354391

2354392

2354393

2354396

2354397

2354398

2354399

2354400

2354401

2354402

2354403

51179

7904396

87921_f_at

90243_f_at

A_14_P132673

A_23_P46105

GE80106

GO:0001561

GO:0003824

GO:0003973

GO:0005515

GO:0005777

GO:0005782

GO:0005829

GO:0006629

GO:0006631

GO:0010181

GO:0016491

GO:0019395

GO:0043226

HMNXSV003022037

ILMN_1740402

ILMN_1767474

PH_hs_0032847

TC01001037.hg

g7705392_3p_a_at

Participates

as a member of

Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)

as a component of

HAO2 tetramer [peroxisomal matrix] (Homo sapiens)

Other forms of this molecule

HAO2 [cytosol]

Inferred To

HAO2 [peroxisomal matrix] (Bos taurus)

HAO2 [peroxisomal matrix] (Caenorhabditis elegans)

HAO2 [peroxisomal matrix] (Canis familiaris)

HAO2 [peroxisomal matrix] (Dictyostelium discoideum)

HAO2 [peroxisomal matrix] (Drosophila melanogaster)

HAO2 [peroxisomal matrix] (Gallus gallus)

HAO2 [peroxisomal matrix] (Mus musculus)

HAO2 [peroxisomal matrix] (Rattus norvegicus)

HAO2 [peroxisomal matrix] (Sus scrofa)

HAO2 [peroxisomal matrix] (Xenopus tropicalis)

Cross References

ENSEMBL

ENSG00000116882, ENST00000361035, ENSP00000316339, ENSP00000354314, ENST00000622548, ENSP00000483507, ENST00000325945

OpenTargets

ENSG00000116882

GeneCards

HAO2

HPA

ENSG00000116882-HAO2

ZINC - Substances

HAOX2_HUMAN

ZINC target

Q9NYQ3

PRO

Q9NYQ3

Pharos - Targets

Q9NYQ3

ZINC - Predictions - Purchasable

HAOX2_HUMAN

HMDB Protein

HMDBP00788

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31948 STIP1	1	STIP1 [cytosol] (R-HSA-443857)	0.527	2
UniProt:P35813 PPM1A	2	PPM1A [nucleoplasm] (R-HSA-205813) PPM1A [cytosol] (R-HSA-380928)	0.527	2
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2
UniProt:Q86US8 SMG6	1	SMG6 [cytosol] (R-HSA-927851)	0.527	2
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.527	2

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