HAO2 tetramer oxidises 2OH-PALM

Stable Identifier
R-HSA-6787811
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Fatty acids can be metabolised by two distinct pathways; alpha- and beta-oxidation. Peroxisomal hydroxyacid oxidase 2 (HAO2) is thought to take part in alpha-oxidation of long chain fatty acids such as 2-hydroxypalmitate (2OH-PALM). HAO2 functions as a homotetramer and is highly expressed in liver and kidney (Jones et al. 2000).

Literature References
PubMed ID Title Journal Year
10777549 Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases

Jones, JM, Morrell, JC, Gould, SJ

J Biol Chem 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity of HAO2 tetramer [peroxisomal matrix]
Physical Entity
Activity
Orthologous Events
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