LIPs hydrolyse TG to DAG and RCOOH

Stable Identifier
R-HSA-6789310
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Lipases are enzymes that hydrolyse dietary lipids such as fats, oils and triglycerides. The majority of human lipases are secreted by the pancreas and function mainly in the digestive system. Lipase members K, M and N (LIPK, M and N), however, all appear to play a role in the last step of keratinocyte differentiation where they are proposed to hydrolyse triglycerides to free fatty acids and glycerol which is essential to stratum corneum hydration (Toulza et al. 2007).
Literature References
PubMed ID Title Journal Year
17562024 Large-scale identification of human genes implicated in epidermal barrier function

Serre, G, Guerrin, M, Jacob, D, Dossat, C, Galliano, MF, de Daruvar, A, Mattiuzzo, NR, Toulza, E, Wincker, P, Jonca, N

Genome Biol. 2007
Participants
Participates
Catalyst Activity

lipoprotein lipase activity of keratinocyte LIPs [extracellular region]

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