Reactome | RPS7 [nucleoplasm]

RPS7 [nucleoplasm]

Stable Identifier

R-HSA-6790635

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S ribosomal protein S7, RS7_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62081 RPS7

Gene Names

RPS7

Chain

chain:1-194

Reference Genes

BioGPS Gene:6201 RPS7

COSMIC (genes):RPS7 RPS7

CTD Gene:6201 RPS7

dbSNP Gene:6201 RPS7

ENSEMBL:ENSG00000171863 RPS7

HGNC:10440 RPS7

KEGG Gene (Homo sapiens):6201 RPS7

Monarch:6201 RPS7

NCBI Gene:6201 RPS7

OMIM:603658 RPS7

UCSC:P62081 RPS7

Reference Transcript

RefSeq:NM_001011.3 RPS7

Other Identifiers

0001580035

11717235_s_at

11717236_x_at

18670223

18670224

18670225

18670227

200082_PM_s_at

200082_s_at

213941_x_at

2467184

2467185

2467186

2467187

2467188

2467189

2467191

2467192

2467196

2467200

2467201

2467205

34646_at

3715611

3715612

3715613

3760488

6201

7892643

7894978

7895808

7896137

8040036

A_23_P141549

GE79310

GO:0000184

GO:0003674

GO:0003723

GO:0003729

GO:0003730

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005840

GO:0005856

GO:0005925

GO:0006364

GO:0006412

GO:0006413

GO:0006464

GO:0006605

GO:0006614

GO:0006810

GO:0007165

GO:0008150

GO:0008219

GO:0009056

GO:0009058

GO:0010628

GO:0015031

GO:0016020

GO:0019083

GO:0019899

GO:0019901

GO:0022627

GO:0030234

GO:0032040

GO:0032991

GO:0034641

GO:0034655

GO:0042254

GO:0042274

GO:0043226

GO:0044403

GO:0048027

GO:0050821

GO:1902255

GO:1904667

GO:1990904

GO:1990948

GO:2000059

Hs.301547.2.S1_3p_x_at

Hs.301547.3.A1_3p_a_at

ILMN_1750722

ILMN_2070072

Z25749_rna1_at

Participant Of

hasComponent

This entity regulates

Positively

30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA

Other forms of this molecule

RPS7 [cytosol]

Inferred To

RPS7 [nucleoplasm] (Bos taurus)

RPS7 [nucleoplasm] (Canis familiaris)

RPS7 [nucleoplasm] (Gallus gallus)

RPS7 [nucleoplasm] (Plasmodium falciparum)

RPS7 [nucleoplasm] (Sus scrofa)

RpS7 [nucleoplasm] (Drosophila melanogaster)

Homologues of RPS7 [nucleoplasm] (Bos taurus)

rps-7 [nucleoplasm] (Caenorhabditis elegans)

RPS7A [nucleoplasm] (Saccharomyces cerevisiae)

rps7 [nucleoplasm] (Danio rerio)

rps7 [nucleoplasm] (Dictyostelium discoideum)

rps7 [nucleoplasm] (Schizosaccharomyces pombe)

rps7 [nucleoplasm] (Xenopus tropicalis)

Rps7 [nucleoplasm] (Mus musculus)

Rps7 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001002.1

Target Pathogen

5b354852be737e166372e9dd

OpenTargets

ENSG00000171863

HPA

ENSG00000171863-RPS7

GeneCards

P62081

Ensembl

ENSP00000495273, ENST00000403564, ENSP00000385286, ENST00000645674, ENSP00000496757, ENSP00000385018, ENST00000406376, ENSG00000171863, ENST00000462576, ENST00000646909, ENSP00000496654

PRO

P62081

Orphanet

17891

PDB

6ZOJ, 5AJ0, 4UG0, 6Y57, 6OLE, 6OM7, 6Y2L, 6G53, 6OM0, 6G51, 6QZP, 6EK0, 5FLX, 5A2Q, 6OLZ, 6G4S, 6Y0G, 5VYC, 6IP8, 6G18, 6G4W, 6OLI, 4V6X, 6FEC, 6IP5, 6IP6, 5T2C, 5LKS, 6G5I, 6OLF, 6G5H, 6OLG, 5OA3

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00987 MDM2	11	SUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472) MDM2 [plasma membrane] (R-HSA-416843) MDM2 [endocytic vesicle membrane] (R-HSA-416849) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) MDM2 [nucleoplasm] (R-HSA-69486) MDM2 [cytosol] (R-HSA-198644) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669)	0.75	15
UniProt:O43829 ZBT14			0.666	4
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:Q15843 NEDD8	17	C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm] (R-HSA-8952504) K1881-CUL9-G76-NEDD8 [cytosol] (R-HSA-8955924) NEDD8 [nucleoplasm] (R-HSA-8955926) K705-CUL4A-G76-NEDD8 [nucleoplasm] (R-HSA-8952528) K859-CUL4B-G76-NEDD8 [nucleoplasm] (R-HSA-8952538) NEDD8(77-88) [cytosol] (R-HSA-6782654) NEDD8(1-88) [cytosol] (R-HSA-5690794) C237-UBA3-G76-NEDD8 [cytosol] (R-HSA-8951647) C116-AcM-UBE2F-G76-NEDD8 [cytosol] (R-HSA-8951739) K720-CUL1-G76-NEDD8 [cytosol] (R-HSA-8952534) K712-CUL3-G76-NEDD8 [cytosol] (R-HSA-8952531) K689-CUL2-G76-NEDD8 [cytosol] (R-HSA-8952526) K724-CUL5-G76-NEDD8 [cytosol] (R-HSA-8952018) NEDD8 [cytosol] (R-HSA-416969) K567-TGFBR2-G76-NEDD8 [cytosol] (R-HSA-4419906) K556-TGFBR2-G76-NEDD8 [cytosol] (R-HSA-4419907) C111-AcM-UBE2M-G76-NEDD8 [cytosol] (R-HSA-4419895)	0.499	2

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