Reactome | RPS2 [nucleoplasm]

RPS2 [nucleoplasm]

Stable Identifier

R-HSA-6790655

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S ribosomal protein S2, RS2_HUMAN

Icon

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P15880 RPS2

Gene Names

RPS2, RPS4

Chain

initiator methionine:1, chain:2-293

Reference Genes

BioGPS Gene:6187 RPS2

COSMIC (genes):RPS2 RPS2

CTD Gene:6187 RPS2

dbSNP Gene:6187 RPS2

ENSEMBL:ENSG00000140988 RPS2

HGNC:10404 RPS2

KEGG Gene (Homo sapiens):6187 RPS2

Monarch:6187 RPS2

NCBI Gene:6187 RPS2

OMIM:603624 RPS2

UCSC:P15880 RPS2

Reference Transcript

RefSeq:NM_002952.3 RPS2

Other Identifiers

0000870035

11756061_x_at

16822889

16822913

16822917

203107_3p_x_at

203107_x_at

212433_x_at

217466_x_at

221798_3p_x_at

221798_x_at

2331692

2331695

2335812

2363662

2373983

2414433

2475662

2491307

2785960

2785961

2787747

2907930

2954754

2954763

31527_at

3322248

3433833

3433834

3433835

3433836

3433837

3433838

3433839

3571878

3581198

3606530

3676302

3676303

3676304

3676308

3676309

3676310

3676313

3676318

3676322

3676324

3748826

3748828

3748829

3748830

3748831

3748832

3748833

3748834

3748836

3763019

3882787

3907385

3907388

4005753

4005754

6187

72997_f_at

7998655

8013348

8172154

89980_s_at

GO:0000184

GO:0003674

GO:0003723

GO:0003729

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006364

GO:0006412

GO:0006413

GO:0006464

GO:0006605

GO:0006614

GO:0006810

GO:0008150

GO:0009056

GO:0009058

GO:0015031

GO:0015935

GO:0016020

GO:0017134

GO:0019083

GO:0019899

GO:0022627

GO:0032991

GO:0034641

GO:0034655

GO:0042254

GO:0043226

GO:0044403

GO:0045202

GO:0045296

GO:0051443

GO:0070062

GO:0071353

Hs.182426.2.S1_3p_x_at

Hs.182426.3.A1_3p_a_at

Hs.182426.4.A1_3p_a_at

ILMN_1688749

ILMN_1737074

ILMN_2133360

ILMN_2218277

PH_hs_0030566

PH_hs_0039080

TC16000768.hg

TC17002540.hg

X17206_at

g4506718_3p_a_at

g4506718_3p_x_at

Participant Of

hasComponent

Other forms of this molecule

Me2aR-RPS2 [cytosol]

RPS2 [cytosol]

Inferred To

Rps2 [nucleoplasm] (Mus musculus)

RpS2 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of RPS2 [nucleoplasm] (Bos taurus)

rps-2 [nucleoplasm] (Caenorhabditis elegans)

RPS2 [nucleoplasm] (Canis familiaris)

RPS2 [nucleoplasm] (Gallus gallus)

RPS2 [nucleoplasm] (Plasmodium falciparum)

RPS2 [nucleoplasm] (Rattus norvegicus)

RPS2 [nucleoplasm] (Saccharomyces cerevisiae)

RPS2 [nucleoplasm] (Sus scrofa)

rps2 [nucleoplasm] (Danio rerio)

rps2 [nucleoplasm] (Dictyostelium discoideum)

rps2 [nucleoplasm] (Schizosaccharomyces pombe)

rps2 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_002943.2

Target Pathogen

5b354852be737e166372e8c8

OpenTargets

ENSG00000140988

GeneCards

P15880

HPA

ENSG00000140988-RPS2

Ensembl

ENSP00000341885, ENSG00000140988, ENST00000343262

PRO

P15880

PDB

4V6X, 6OLE, 6ZOJ, 6OM7, 6Y57, 5FLX, 6OLZ, 6EK0, 6G53, 4UG0, 5VYC, 5AJ0, 6IP5, 5OA3, 6G5H, 5A2Q, 6OLF, 5LKS, 6IP8, 6IP6, 6Y2L, 6OLI, 6G18, 6G5I, 5T2C, 6OLG, 6QZP, 6OM0, 6Y0G, 6G51, 6G4S

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60678 PRMT3	1	PRMT3 [cytosol] (R-HSA-8876692)	0.75	5
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.642	4
UniProt:Q9H0A0 NAT10	1	NAT10 [nucleoplasm] (R-HSA-6791008)	0.564	2
UniProt:P60520 GABARAPL2	3	GABARAPL2(1-117) [cytosol] (R-HSA-5682641) GABARAPL2 [cytosol] (R-HSA-5671758) GABARAPL2 [autophagosome membrane] (R-HSA-5683633)	0.547	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P03372 ESR1	8	SUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) Me260-ESR1 [cytosol] (R-HSA-9632177) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.462	2