NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447

Stable Identifier
R-HSA-6790944
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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NOP2 methylates the carbon at the 5th position of the cytosine ring at cytidine-4447 in 28S rRNA (Bourgeois et al. 2015). NOP2 also has a role in rRNA processing that is independent of its methylase activity.

Literature References
PubMed ID Title Journal Year
26196125 Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120

Bourgeois, G, Ney, M, Gaspar, I, Aigueperse, C, Schaefer, M, Kellner, S, Helm, M, Motorin, Y

PLoS ONE 2015
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Go Biological Process
Catalyst Activity
Catalyst Activity
Title
rRNA (cytosine-C5-)-methyltransferase activity of NOP2 [nucleoplasm]
Physical Entity
Activity
Inferred From
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Created