Release of NS1 homodimer

Stable Identifier
R-HSA-6791035
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
Locations in the PathwayBrowser
General
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Once the NS1 homodimer is imported into the nucleus, the importin complex releases the NS1 homodimer.

Literature References
PubMed ID Title Journal Year
10846107 Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication

Bergmann, M, Garcia-Sastre, A, Carnero, E, Pehamberger, H, Wolff, K, Palese, P, Muster, T

J. Virol. 2000
10205180 Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery

Chen, Z, Li, Y, Krug, RM

EMBO J 1999
9651582 Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs

Nemeroff, ME, Barabino, SM, Li, Y, Keller, W, Krug, RM

Mol Cell 1998
8313914 Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport

Fortes, P, Beloso, A, Ortin, J

EMBO J 1994
Participants
Participant Of
Disease
Name Identifier Synonyms
influenza 8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Authored
Reviewed
Created