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RPS3A [nucleoplasm]
Stable Identifier
R-HSA-6791182
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="2"40S ribosomal protein S3a, RS3A_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
RPS3A [nucleoplasm] (Homo sapiens)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)
RPS3A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P61247 RPS3A
Gene Names
RPS3A, FTE1, MFTL
Chain
initiator methionine:, chain:2-264
Reference Genes
BioGPS Gene:6189 RPS3A
COSMIC (genes):RPS3A RPS3A
CTD Gene:6189 RPS3A
dbSNP Gene:6189 RPS3A
ENSEMBL:ENSG00000145425 RPS3A
HGNC:10421 RPS3A
KEGG:hsa:6189 RPS3A
Monarch:6189 RPS3A
NCBI Gene:6189 RPS3A
OMIM:180478 RPS3A
UCSC:P61247 RPS3A
Reference Transcript
RefSeq:NM_001006.4 RPS3A
Other Identifiers
11716320_x_at
11762787_x_at
1653_at
16652759
16652761
16652763
16652765
16652767
16652777
16971413
16971433
17119388
18670013
18670014
18670015
18670016
18670017
18670018
18670019
18670020
18670021
18670022
18670023
18670024
18670025
18670026
18670027
18670028
18670029
18670030
200099_PM_s_at
200099_s_at
201257_PM_x_at
201257_x_at
212391_PM_x_at
212391_x_at
2612273
2640149
2683221
2747386
2747387
2747388
2747389
2747390
2747391
2747392
2747394
2747395
2747396
2747397
2747398
2747399
2747400
2747401
2747402
2747403
2747404
2747405
2747406
2864020
2864032
2870769
2870772
3061872
3061877
3062954
3062956
3062958
3062959
3062962
3062963
3084158
3084759
3122846
3124697
3124911
3255508
3255510
3255512
3259229
3359842
3379154
3482604
3596234
3596235
3596236
3621007
3621014
3790794
3790796
3957133
6189
7894205
7894971
7894982
7988031
8097782
8097790
8097792
8103222
8141050
8141222
A_14_P201526
A_21_P0000207
A_23_P144497
GE79078
GE86759
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005783
GO:0005829
GO:0005840
GO:0005925
GO:0006412
GO:0006413
GO:0022626
GO:0022627
GO:0030154
GO:0032040
GO:0042274
GO:0043066
GO:0043226
GO:0045202
GO:0048027
GO:0070062
GO:1990904
HMNXSV003004860
HMNXSV003011773
HMNXSV003018368
Hs.77039.1.S1_3p_x_at
ILMN_1657722
ILMN_1667288
ILMN_1673638
ILMN_2139943
M84711_at
PH_hs_0029871
RNA33685|snoRNA_scaRNA_281_75
RNA33778|snoRNA_scaRNA_374_65
TC04000748.hg
TC04000749.hg
g4506722_3p_x_at
Participates
as a component of
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
This entity regulates
Positively
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA
(Homo sapiens)
Other forms of this molecule
RPS3A [cytosol]
Inferred To
RPS3A [nucleoplasm]
(Bos taurus)
RPS3A [nucleoplasm]
(Canis familiaris)
RPS3A [nucleoplasm]
(Plasmodium falciparum)
RPS3A [nucleoplasm]
(Sus scrofa)
RpS3A [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of RPS3A [nucleoplasm]
(Gallus gallus)
RPS1B [nucleoplasm]
(Saccharomyces cerevisiae)
rps-1 [nucleoplasm]
(Caenorhabditis elegans)
rps101 [nucleoplasm]
(Schizosaccharomyces pombe)
Rps3a [nucleoplasm]
(Mus musculus)
Rps3a [nucleoplasm]
(Rattus norvegicus)
rps3a [nucleoplasm]
(Danio rerio)
rps3a [nucleoplasm]
(Dictyostelium discoideum)
rps3a [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000997.1
ENSEMBL
ENST00000709893
,
ENSP00000517921
,
ENST00000274065
,
ENSP00000346050
OpenTargets
ENSG00000145425
HPA
ENSG00000145425-RPS3A
PRO
P61247
Pharos - Targets
P61247
GlyGen
P61247
PDB
6ZOK
,
6IP8
,
8JDM
,
8XXN
,
4V6X
,
6XA1
,
8XXL
,
8OZ0
,
7WU0
,
8G5Y
,
5A2Q
,
5T2C
,
6ZXE
,
5AJ0
,
7WTS
,
8G6J
,
7WTZ
,
7QVP
,
6ZOJ
,
6ZVJ
,
8T4S
,
5VYC
,
7WTW
,
7XNY
,
8Y0X
,
6YBW
,
7A09
,
6OM0
,
6ZM7
,
8PPL
,
6IP5
,
6YBD
,
6OLE
,
8G61
,
8JDL
,
7R4X
,
6QZP
,
6ZP4
,
6ZME
,
6G5H
,
6ZXG
,
6G18
,
6ZMI
,
6G4W
,
7MQA
,
8IFD
,
6ZMO
,
7XNX
,
6Z6N
,
6G53
,
8G60
,
8JDK
,
8G5Z
,
6FEC
,
7QP7
,
6IP6
,
6OLF
,
6ZXH
,
6Y57
,
8XXM
,
7MQ9
,
8GLP
,
7TQL
,
6G5I
,
7MQ8
,
5LKS
,
7WTV
,
7K5I
,
7WTX
,
6ZVH
,
6OLZ
,
7WTU
,
6G4S
,
6G51
,
6ZN5
,
6Z6L
,
6ZLW
,
6OLG
,
6ZON
,
5FLX
,
7QP6
,
8PPK
,
8Y0W
,
8JDJ
,
6ZXF
,
5OA3
,
6Y2L
,
6OLI
,
6ZXD
,
6ZUO
,
6OM7
,
6ZV6
,
6ZMW
,
6Y0G
,
4UG0
,
7WTT
,
8QOI
,
6ZMT
,
6Z6M
,
8IFE
Interactors (29)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62263 RPS14
2
RPS14 [cytosol]
(R-HSA-72333)
RPS14 [nucleoplasm]
(R-HSA-6790669)
0.669
4
UniProt:P07900 HSP90AA1
8
HSP90AA1 [lysosomal lumen]
(R-HSA-9622850)
HSP90AA1 [cytosol]
(R-HSA-192864)
HSP90AA1 [nucleoplasm]
(R-HSA-5082401)
HSP90AA1 [plasma membrane]
(R-HSA-534996)
HSP90AA1 [secretory granule lumen]
(R-HSA-6801515)
HSP90AA1 [extracellular region]
(R-HSA-3221946)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-HSA-6801470)
HSP90AA1 [endocytic vesicle lumen]
(R-HSA-3221912)
0.635
3
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.569
9
UniProt:Q9NX58 LYAR
0.564
2
UniProt:P62906 RPL10A
1
RPL10A [cytosol]
(R-HSA-72404)
0.564
2
UniProt:P62241 RPS8
2
RPS8 [cytosol]
(R-HSA-72385)
RPS8 [nucleoplasm]
(R-HSA-6791203)
0.527
3
UniProt:P15880 RPS2
3
RPS2 [cytosol]
(R-HSA-72347)
Me2aR-RPS2 [cytosol]
(R-HSA-8879138)
RPS2 [nucleoplasm]
(R-HSA-6790655)
0.527
3
UniProt:P62280 RPS11
2
RPS11 [cytosol]
(R-HSA-72327)
RPS11 [nucleoplasm]
(R-HSA-6791212)
0.527
2
UniProt:P16104 H2AFX
7
H2AFX [nucleoplasm]
(R-HSA-56151)
p-Y143-H2AFX [nucleoplasm]
(R-HSA-5683942)
p-S140,Y143-H2AFX [nucleoplasm]
(R-HSA-5683953)
p-S140-H2AFX [nucleoplasm]
(R-HSA-75170)
K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm]
(R-HSA-5682847)
H2AFX [extracellular region]
(R-HSA-977583)
Me2sR4-H2AFX [nucleoplasm]
(R-HSA-5218317)
0.527
2
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.527
4
UniProt:Q96HE9 PRR11
0.527
2
UniProt:Q96ME7 ZN512
0.527
2
UniProt:P10412 H1-4
1
HIST1H1E [nucleoplasm]
(R-HSA-211251)
0.527
2
UniProt:Q1ED39 KNOP1
0.527
2
UniProt:O95793 STAU1
0.527
2
UniProt:Q8TBF4 ZCRB1
2
ZCRB1 [cytosol]
(R-HSA-9682010)
ZCRB1 [nucleoplasm]
(R-HSA-6787853)
0.527
3
UniProt:P17026 ZNF22
0.527
2
UniProt:Q15397 PUM3
0.527
2
UniProt:Q15050 RRS1
0.527
2
UniProt:Q9NZM5 NOP53
0.527
2
UniProt:P42696 RBM34
0.527
2
UniProt:P61513 RPL37A
1
RPL37A [cytosol]
(R-HSA-72468)
0.527
2
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.495
2
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
12
UniProt:P62753 RPS6
4
RPS6 [cytosol]
(R-HSA-72381)
p-5S-RPS6 [cytosol]
(R-HSA-165727)
3OHR147-RPS6 [cytosol]
(R-HSA-9629876)
RPS6 [nucleoplasm]
(R-HSA-6790606)
0.483
4
UniProt:P26196 DDX6
1
DDX6 [cytosol]
(R-HSA-430032)
0.483
2
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.462
2
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