Reactome | RPS16 [nucleoplasm]

RPS16 [nucleoplasm]

Stable Identifier

R-HSA-6791196

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S ribosomal protein S16, RS16_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62249 RPS16

Gene Names

RPS16

Chain

initiator methionine:1, chain:2-146

Reference Genes

BioGPS Gene:6217 RPS16

COSMIC (genes):RPS16 RPS16

CTD Gene:6217 RPS16

dbSNP Gene:6217 RPS16

ENSEMBL:ENSG00000105193 RPS16

ENSEMBL:ENSG00000105193.9 RPS16

HGNC:10396 RPS16

KEGG Gene (Homo sapiens):6217 RPS16

Monarch:6217 RPS16

NCBI Gene:6217 RPS16

OMIM:603675 RPS16

UCSC:P62249 RPS16

Reference Transcript

RefSeq:NM_001020.5 RPS16

Other Identifiers

11758289_x_at

16872229

201258_PM_at

201258_at

213890_PM_x_at

213890_x_at

226131_PM_s_at

226131_s_at

38061_at

3862019

3862020

3862021

3862022

3862024

3862026

3862029

3862030

3862031

3862032

6217

8036737

A_23_P208850

GE80063

GE88165

GO:0000462

GO:0002181

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006364

GO:0006412

GO:0015935

GO:0016020

GO:0022626

GO:0022627

GO:0032040

GO:0042254

GO:0042274

GO:0043226

GO:0045202

GO:0070062

GO:1990830

GO:1990904

HMNXSV003030940

Hs.80617.2.S1_3p_x_at

ILMN_1651850

M60854_at

TC19001521.hg

g4506690_3p_a_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

This entity regulates

Positively

30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)

Other forms of this molecule

RPS16 [cytosol]

Inferred To

Homologues of RPS16 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of RPS16 [nucleoplasm] (Schizosaccharomyces pombe)

Rps16 [nucleoplasm] (Mus musculus)

Rps16 [nucleoplasm] (Rattus norvegicus)

im:6906552 [nucleoplasm] (Danio rerio)

rps16 [nucleoplasm] (Dictyostelium discoideum)

rps16 [nucleoplasm] (Xenopus tropicalis)

rps-16 [nucleoplasm] (Caenorhabditis elegans)

rps1601 [nucleoplasm] (Schizosaccharomyces pombe)

RPS16 [nucleoplasm] (Bos taurus)

RPS16 [nucleoplasm] (Gallus gallus)

RPS16 [nucleoplasm] (Plasmodium falciparum)

RPS16 [nucleoplasm] (Sus scrofa)

RPS16B [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of RPS16 [nucleoplasm] (Canis familiaris)

RPS16A [nucleoplasm] (Saccharomyces cerevisiae)

RpS16 [nucleoplasm] (Drosophila melanogaster)

rps1602 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001011.1

OpenTargets

ENSG00000105193

HPA

ENSG00000105193-RPS16

GeneCards

P62249

Ensembl

ENST00000251453, ENSP00000251453, ENSG00000105193

PRO

P62249

Pharos - Targets

P62249

PDB

6G18, 6G5H, 6ZLW, 6Z6M, 6IP5, 5VYC, 6OLG, 6ZM7, 6IP6, 7A09, 6ZXE, 6G4S, 4V6X, 7K5I, 7QP6, 6ZOL, 6ZXF, 6ZME, 6ZON, 6G51, 7WTV, 6OLZ, 6OM0, 5A2Q, 6ZXH, 7MQ8, 7WTU, 6ZMI, 7WU0, 4UG0, 7WTX, 6OM7, 6FEC, 5AJ0, 6Z6L, 6OLF, 6ZOJ, 6ZMW, 5T2C, 6XA1, 5LKS, 6ZN5, 6Z6N, 6ZVH, 7WTT, 6G5I, 6OLI, 6ZVJ, 6ZXD, 6Y0G, 6IP8, 6G4W, 6ZP4, 6ZXG, 6QZP, 7R4X, 7TQL, 6ZUO, 5FLX, 7MQ9, 6G53, 6YBS, 6Y2L, 7QP7, 6ZMO, 6Y57, 7WTZ, 6ZV6, 6ZMT, 7MQA, 7WTW, 5OA3, 6OLE

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.642	4
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.607	3
UniProt:Q15843 NEDD8	8	C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm] (R-HSA-8952504) NEDD8 [nucleoplasm] (R-HSA-8955926) C116-AcM-UBE2F-G76-NEDD8 [cytosol] (R-HSA-8951739) NEDD8(77-88) [cytosol] (R-HSA-6782654) NEDD8(1-88) [cytosol] (R-HSA-5690794) C237-UBA3-G76-NEDD8 [cytosol] (R-HSA-8951647) NEDD8 [cytosol] (R-HSA-416969) C111-AcM-UBE2M-G76-NEDD8 [cytosol] (R-HSA-4419895)	0.527	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	12
UniProt:Q92731 ESR2	5	PalmS-ESR2 [cytosol] (R-HSA-9020979) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) ESR2 [nucleoplasm] (R-HSA-446165) ESR2 [cytosol] (R-HSA-9020970)	0.462	2
UniProt:P03372 ESR1	8	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.462	2

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