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RPS8 [nucleoplasm]
Stable Identifier
R-HSA-6791203
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
40S ribosomal protein S8, RS8_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
RPS8 [nucleoplasm] (Homo sapiens)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)
RPS8 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62241 RPS8
Gene Names
RPS8, OK/SW-cl.83
Chain
initiator methionine:1, chain:2-208
Reference Genes
BioGPS Gene:6202 RPS8
COSMIC (genes):RPS8 RPS8
CTD Gene:6202 RPS8
dbSNP Gene:6202 RPS8
ENSEMBL:ENSG00000142937 RPS8
HGNC:10441 RPS8
KEGG Gene (Homo sapiens):6202 RPS8
Monarch:6202 RPS8
NCBI Gene:6202 RPS8
OMIM:600357 RPS8
Reference Transcript
RefSeq:NM_001012.1 RPS8
Other Identifiers
0006760168
11715543_x_at
16663989
200858_s_at
2334165
2334166
2334170
2334174
2334175
2334176
2334179
2334180
2334184
2334189
2334190
2805737
2805739
2805742
31583_at
3203916
3203922
3582023
3613011
3613012
6202
74705_s_at
7901038
A_23_P46182
GO:0000184
GO:0000462
GO:0003674
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005829
GO:0005840
GO:0005925
GO:0006412
GO:0006413
GO:0006605
GO:0006614
GO:0006810
GO:0008150
GO:0009056
GO:0009058
GO:0015031
GO:0016020
GO:0019083
GO:0022627
GO:0032991
GO:0034641
GO:0034655
GO:0042254
GO:0043226
GO:0044403
GO:0070062
GO:1990904
ILMN_1656203
ILMN_3243700
PH_hs_0034351
X67247_rna1_at
g4506742_3p_s_at
Participant Of
hasComponent
18SE pre-40S particle [nucleoplasm]
This entity regulates
Positively
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA
Other forms of this molecule
RPS8 [cytosol]
Inferred To
RPS8A [nucleoplasm] (Saccharomyces cerevisiae)
Rps8 [nucleoplasm] (Mus musculus)
Rps8 [nucleoplasm] (Rattus norvegicus)
rps8 [nucleoplasm] (Dictyostelium discoideum)
rps8 [nucleoplasm] (Xenopus tropicalis)
RPS8 [nucleoplasm] (Canis familiaris)
RPS8 [nucleoplasm] (Plasmodium falciparum)
RPS8 [nucleoplasm] (Sus scrofa)
rps-8 [nucleoplasm] (Caenorhabditis elegans)
rps8b [nucleoplasm] (Danio rerio)
RpS8 [nucleoplasm] (Drosophila melanogaster)
Homologues of RPS8 [nucleoplasm] (Saccharomyces cerevisiae)
RPS8B [nucleoplasm] (Saccharomyces cerevisiae)
rps802 [nucleoplasm] (Schizosaccharomyces pombe)
Cross References
RefSeq
NP_001003.1
Target Pathogen
5b354852be737e166372e98e
OpenTargets
ENSG00000142937
HPA
ENSG00000142937-RPS8
GeneCards
P62241
Ensembl
ENSG00000142937
,
ENST00000396651
,
ENSP00000379888
PRO
P62241
PDB
6G53
,
6EK0
,
5A2Q
,
6G4W
,
5FLX
,
6OLE
,
4V6X
,
6G4S
,
6G18
,
6OLF
,
6Y0G
,
5LKS
,
6Y2L
,
5T2C
,
6OLG
,
5VYC
,
6FEC
,
6OLI
,
6G5H
,
6IP5
,
6G5I
,
6IP6
,
6OM0
,
5OA3
,
6ZOJ
,
6QZP
,
6Y57
,
6IP8
,
6OLZ
,
5AJ0
,
4UG0
,
6OM7
,
6G51
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92796 DLG3
2
DLG3 [cytosol]
(R-HSA-6794232)
DLG3 [plasma membrane]
(R-HSA-443609)
0.556
3
UniProt:Q15700 DLG2
2
DLG2 [plasma membrane]
(R-HSA-9610662)
DLG2 [cytosol]
(R-HSA-6794230)
0.556
3
UniProt:Q15843 NEDD8
17
C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm]
(R-HSA-8952504)
K1881-CUL9-G76-NEDD8 [cytosol]
(R-HSA-8955924)
NEDD8 [nucleoplasm]
(R-HSA-8955926)
K705-CUL4A-G76-NEDD8 [nucleoplasm]
(R-HSA-8952528)
K859-CUL4B-G76-NEDD8 [nucleoplasm]
(R-HSA-8952538)
NEDD8(77-88) [cytosol]
(R-HSA-6782654)
NEDD8(1-88) [cytosol]
(R-HSA-5690794)
C237-UBA3-G76-NEDD8 [cytosol]
(R-HSA-8951647)
C116-AcM-UBE2F-G76-NEDD8 [cytosol]
(R-HSA-8951739)
K720-CUL1-G76-NEDD8 [cytosol]
(R-HSA-8952534)
K712-CUL3-G76-NEDD8 [cytosol]
(R-HSA-8952531)
K689-CUL2-G76-NEDD8 [cytosol]
(R-HSA-8952526)
K724-CUL5-G76-NEDD8 [cytosol]
(R-HSA-8952018)
NEDD8 [cytosol]
(R-HSA-416969)
K567-TGFBR2-G76-NEDD8 [cytosol]
(R-HSA-4419906)
K556-TGFBR2-G76-NEDD8 [cytosol]
(R-HSA-4419907)
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(R-HSA-4419895)
0.527
2
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P03372 ESR1
8
SUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
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