Reactome | RPS11 [nucleoplasm]

RPS11 [nucleoplasm]

Stable Identifier

R-HSA-6791212

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S ribosomal protein S11, RS11_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P63151 PPP2R2A

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External Reference Information

External Reference

UniProt:P62280 RPS11

Gene Names

RPS11

Chain

initiator methionine:1, chain:2-158

Reference Genes

BioGPS Gene:6205 RPS11

COSMIC (genes):RPS11 RPS11

CTD Gene:6205 RPS11

dbSNP Gene:6205 RPS11

ENSEMBL:ENSG00000142534 RPS11

HGNC:10384 RPS11

KEGG Gene (Homo sapiens):6205 RPS11

Monarch:6205 RPS11

NCBI Gene:6205 RPS11

OMIM:180471 RPS11

UCSC:P62280 RPS11

Reference Transcript

RefSeq:NM_001015.4 RPS11

Other Identifiers

11715376_a_at

11745362_x_at

16864159

18671238

18671239

18671241

18671242

200031_PM_s_at

200031_s_at

32330_at

3439259

3439262

3439263

3838608

3838609

3838612

3838615

3838619

3838620

6205

7893727

7893956

7894634

7894999

7895762

8030368

GE78949

GO:0000184

GO:0003674

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006412

GO:0006413

GO:0006605

GO:0006614

GO:0006810

GO:0008150

GO:0009056

GO:0009058

GO:0015031

GO:0016020

GO:0019083

GO:0019843

GO:0022627

GO:0032991

GO:0034641

GO:0034655

GO:0043226

GO:0044403

GO:0070062

ILMN_1740587

PH_hs_0030181

TC19000735.hg

X06617_at

g4506680_3p_a_at

Participant Of

hasComponent

18SE pre-40S particle [nucleoplasm]

This entity regulates

Positively

30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA

Other forms of this molecule

RPS11 [cytosol]

Inferred To

Homologues of RPS11 [nucleoplasm] (Canis familiaris)

Homologues of RPS11 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of RPS11 [nucleoplasm] (Schizosaccharomyces pombe)

RpS11 [nucleoplasm] (Drosophila melanogaster)

RPS11A [nucleoplasm] (Saccharomyces cerevisiae)

rps1102 [nucleoplasm] (Schizosaccharomyces pombe)

RPS11 [nucleoplasm] (Canis familiaris)

RPS11 [nucleoplasm] (Plasmodium falciparum)

RPS11 [nucleoplasm] (Sus scrofa)

RPS11 [nucleoplasm] (Xenopus tropicalis)

RPS11B [nucleoplasm] (Saccharomyces cerevisiae)

rps11 [nucleoplasm] (Danio rerio)

rps11 [nucleoplasm] (Dictyostelium discoideum)

rps-11 [nucleoplasm] (Caenorhabditis elegans)

rps1101 [nucleoplasm] (Schizosaccharomyces pombe)

Rps11 [nucleoplasm] (Mus musculus)

Rps11 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001006.1

Target Pathogen

5b354852be737e166372eb10

OpenTargets

ENSG00000142534

GeneCards

P62280

HPA

ENSG00000142534-RPS11

Ensembl

ENSG00000142534, ENST00000270625, ENSP00000270625

PRO

P62280

PDB

6OLZ, 6QZP, 6EK0, 6OM0, 5A2Q, 5FLX, 6G53, 6Y57, 6ZOJ, 6OM7, 5AJ0, 4UG0, 6OLE, 6OLF, 6FEC, 6IP5, 6G5H, 5OA3, 6OLG, 6IP6, 6OLI, 5T2C, 5LKS, 6G5I, 6G18, 6G4S, 5VYC, 6IP8, 4V6X, 6Y0G, 6Y2L, 6G51, 6G4W

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.642	5
UniProt:Q99558 MAP3K14	5	MAP3K14 [cytosol] (R-HSA-168189) Active NIK [cytosol] (R-HSA-5607646) p-MAP3K14 [cytosol] (R-HSA-168187) K48polyUb-NIK [cytosol] (R-HSA-5668525) p-T559-MAP3K14 [cytosol] (R-HSA-5668531)	0.564	3
UniProt:Q96T49 PP16B			0.462	2
UniProt:Q92731 ESR2	5	PalmS-ESR2 [plasma membrane] (R-HSA-9021059) PalmS-ESR2 [cytosol] (R-HSA-9020979) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) ESR2 [nucleoplasm] (R-HSA-446165) ESR2 [cytosol] (R-HSA-9020970)	0.462	2
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.462	2
UniProt:Q00005 2ABB			0.462	2
UniProt:P63151 PPP2R2A	2	PPP2R2A [nucleoplasm] (R-HSA-1564978) PPP2R2A [cytosol] (R-HSA-377253)	0.462	2

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