Reactome: A Curated Pathway Database

GADD45A binds AURKA

Stable Identifier
R-HSA-6791235
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

GADD45A binds Aurora-A protein kinase (AURKA). GADD45A inhibits the kinase activity of AURKA and AURKA-induced centrosome amplification, thus interfering with the G2/M transition (Shao et al. 2006, Sanchez et al. 2010).

Literature References
Participants
Participant Of
Orthologous Events