MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145

Stable Identifier
R-HSA-6793122
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
MRM1 located in foci near mitochondrial nucleoids (Lee et al. 2013) transfers a methyl group from S-adenosylmethionine to the 2' hydroxyl of guanosine-1145 in 16S rRNA (Lee and Bogenhagen 2014).
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Event Information
Go Biological Process
rRNA 2'-O-methylation (0000451)
Catalyst Activity

rRNA (guanosine-2'-O-)-methyltransferase activity of MRM1 [mitochondrial matrix]

Physical Entity
MRM1 [mitochondrial matrix] (Homo sapiens)
Activity
rRNA (guanosine-2'-O-)-methyltransferase activity (GO:0070039)
Authored
May, B  (2015-08-30)
Reviewed
Bogenhagen, DF  (2016-04-25)
Created
May, B  (2015-08-31)
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