Reactome: A Curated Pathway Database

MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145

Stable Identifier
R-HSA-6793122
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

MRM1 located in foci near mitochondrial nucleoids (Lee et al. 2013) transfers a methyl group from S-adenosylmethionine to the 2' hydroxyl of guanosine-1145 in 16S rRNA (Lee and Bogenhagen 2014).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
rRNA (guanosine-2'-O-)-methyltransferase activity of MRM1 [mitochondrial matrix] MRM1 [mitochondrial matrix] rRNA (guanosine-2'-O-)-methyltransferase activity (0070039)