Expression of GATA3

Stable Identifier
R-HSA-6793975
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
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Expression of GATA3
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Phosphorylated Signal transducer and activator of transcription 6 (STAT6) dimers translocate to the nucleus and activate the transcription of several genes including the nuclear protein Trans-acting T-cell-specific transcription factor GATA-3 (Takeda et al. 1994, Park et al. 1998).

Literature References
PubMed ID Title Journal Year
9736340 Interferon-gamma-induced factor binding to the interleukin-4-responsive element of CD23b promoter in human tonsillar mononuclear cells: role in transient up-regulation of the interleukin-4-induced CD23b mRNA

Park, HJ, So, EY, Lee, CE

Mol. Immunol. 1998
8602263 Essential role of Stat6 in IL-4 signalling

Takeda, K, Tanaka, T, Shi, W, Matsumoto, M, Minami, M, Kashiwamura, S, Nakanishi, K, Yoshida, N, Kishimoto, T, Akira, S

Nature 1996
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Output
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as an event of
This event is regulated
Positively by
Regulator
p-Y641-STAT6 dimer [nucleoplasm] (Homo sapiens)
Authored
Jupe, S  (2015-07-01)
Reviewed
Leibovich, SJ  (2016-09-02)
Created
Jupe, S  (2015-09-04)
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