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SHANK1 [cytosol]
Stable Identifier
R-HSA-6794274
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SH3 and multiple ankyrin repeat domains protein 1, SHAN1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Neurexins and neuroligins (Homo sapiens)
ABP1 binds SHANK proteins (Homo sapiens)
NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Homo sapiens)
SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1 [cytosol] (Homo sapiens)
NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3:DBNL [cytosol] (Homo sapiens)
NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Homo sapiens)
SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1 [cytosol] (Homo sapiens)
HOMER binds SHANK proteins (Homo sapiens)
NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Homo sapiens)
SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1 [cytosol] (Homo sapiens)
NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3:2xHOMER1,2,3:GRM1,5 [plasma membrane] (Homo sapiens)
NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Homo sapiens)
SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1 [cytosol] (Homo sapiens)
SHANK proteins bind GKAPs (Homo sapiens)
NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Homo sapiens)
SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1 [cytosol] (Homo sapiens)
SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1 [cytosol] (Homo sapiens)
SHARPIN binds SHANK proteins (Homo sapiens)
SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1 [cytosol] (Homo sapiens)
SHARPIN:SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1,2,3 [cytosol] (Homo sapiens)
SHANK1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y566 SHANK1
Gene Names
SHANK1
Chain
chain:1-2161
Reference Genes
BioGPS Gene:50944 SHANK1
COSMIC (genes):SHANK1 SHANK1
CTD Gene:50944 SHANK1
dbSNP Gene:50944 SHANK1
ENSEMBL:ENSG00000161681 SHANK1
HGNC:15474 SHANK1
KEGG Gene (Homo sapiens):50944 SHANK1
Monarch:50944 SHANK1
NCBI Gene:50944 SHANK1
OMIM:604999 SHANK1
UCSC:Q9Y566 SHANK1
Reference Transcript
RefSeq:NM_016148.3 SHANK1
RefSeq:XM_011527014.2 SHANK1
RefSeq:XM_006723233.3 SHANK1
Other Identifiers
0002570575
11738107_a_at
16874604
220563_s_at
3868588
3868589
3868590
3868591
3868595
3868596
3868597
3868598
3868599
3868600
3868601
3868602
3868603
3868604
3868605
3868609
3868610
3868611
3868613
3868614
3868615
3868616
3868617
3868621
3868622
3868623
3868625
3868626
3868627
3868628
3868631
3868632
3868633
3868634
3868635
3868636
3868638
3868639
50944
8038598
A_23_P208636
GE83980
GE843136
GO:0000902
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0006810
GO:0007010
GO:0007165
GO:0007267
GO:0007399
GO:0007416
GO:0007616
GO:0008022
GO:0008150
GO:0008306
GO:0008328
GO:0014069
GO:0016020
GO:0017124
GO:0017146
GO:0021700
GO:0022607
GO:0030054
GO:0030154
GO:0030159
GO:0030160
GO:0030425
GO:0030534
GO:0030674
GO:0031877
GO:0032232
GO:0032991
GO:0034330
GO:0035176
GO:0035255
GO:0035418
GO:0040007
GO:0042048
GO:0042802
GO:0043005
GO:0043197
GO:0043226
GO:0044309
GO:0044877
GO:0045202
GO:0045211
GO:0046959
GO:0048854
GO:0048856
GO:0050877
GO:0050885
GO:0050894
GO:0051124
GO:0051968
GO:0055085
GO:0060013
GO:0060074
GO:0060076
GO:0060291
GO:0060997
GO:0060999
GO:0065003
GO:0071532
GO:0071625
GO:0097107
GO:0097110
GO:0098978
GO:2000311
GO:2000463
ILMN_1747754
PH_hs_0032418
TC19001752.hg
TC19002552.hg
g11968151_3p_a_at
Participant Of
hasMember
SHANK1,2,3 [cytosol]
Inferred To
shank1 [cytosol] (Xenopus tropicalis)
Prosap [cytosol] (Drosophila melanogaster)
shn-1 [cytosol] (Caenorhabditis elegans)
Shank1 [cytosol] (Mus musculus)
Shank1 [cytosol] (Rattus norvegicus)
SHANK1 [cytosol] (Canis familiaris)
Cross References
RefSeq
XP_006723296.1
,
XP_011525316.1
,
NP_057232.2
OpenTargets
ENSG00000161681
GeneCards
Q9Y566
HPA
ENSG00000161681-SHANK1
Ensembl
ENSP00000375689
,
ENSP00000351984
,
ENST00000391813
,
ENSP00000293441
,
ENST00000359082
,
ENST00000293441
,
ENSG00000161681
PRO
Q9Y566
Orphanet
24896
PDB
6CPI
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