Reactome: A Curated Pathway Database

TORC2 complex phosphorylates SGK1

Stable Identifier
R-HSA-6795290
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The TORC2 complex phosphorylates SGK1 at serine residue S422, located in the carboxy-terminal hydrophobic motif of SGK1. Phosphorylation at S422 contributes to SGK1 activation (Garcia-Martinez and Alessi 2008, Lu et al. 2010).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein serine/threonine kinase activity of TORC2 complex [cytosol] TORC2 complex [cytosol] protein serine/threonine kinase activity (0004674)
Orthologous Events