There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime
Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17
SGK1 phosphorylates MDM2 at serine residues S166 and S188, resulting in MDM2 activation (Amato et al. 2009, Lyo et al. 2010). SGK1 may play a more prominent role in MDM2 activation than AKT (Lyo et al. 2010).