Reactome: A Curated Pathway Database

TP53 and E2F4 inhibit CDC25C expression

Stable Identifier
R-HSA-6798268
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Binding of TP53 and the E2F4 repressor complex to the promoter of the CDC25C gene results in the inhibition of CDC25C transcription, an important step in the maintenance of the G2 cell cycle checkpoint (St. Clair et al. 2004, Benson et al. 2014).

Literature References
Participants
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