Reactome | RPS18 [nucleoplasm]

RPS18 [nucleoplasm]

Stable Identifier

R-HSA-6798701

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S small ribosomal protein 18, P25232, 40S ribosomal protein S18, KE-3, KE3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P62269 RPS18

Gene Names

RPS18, D6S218E

Chain

initiator methionine:1, chain:2-152

Reference Genes

BioGPS Gene:6222 RPS18

COSMIC (genes):RPS18 RPS18

CTD Gene:6222 RPS18

dbSNP Gene:6222 RPS18

ENSEMBL:ENSG00000096150 RPS18

ENSEMBL:ENSG00000223367 RPS18

ENSEMBL:ENSG00000226225 RPS18

ENSEMBL:ENSG00000231500 RPS18

ENSEMBL:ENSG00000235650 RPS18

HGNC:10401 RPS18

KEGG Gene (Homo sapiens):6222 RPS18

Monarch:6222 RPS18

NCBI Gene:6222 RPS18

OMIM:180473 RPS18

UCSC:P62269 RPS18

Reference Transcript

RefSeq:NM_022551.2 RPS18

Other Identifiers

0003120167

11756437_x_at

17041345

201049_s_at

2686718

2686719

2686720

2686721

2686724

2903558

2903562

2903567

2903569

2903571

2903573

2930816

31545_at

3548492

3746486

6222

8118644

8178253

8179544

A_14_P121071

A_23_P214666

GE508175

GO:0000184

GO:0003674

GO:0003676

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006412

GO:0006413

GO:0006605

GO:0006614

GO:0006810

GO:0008150

GO:0009056

GO:0009058

GO:0015031

GO:0015935

GO:0016020

GO:0019083

GO:0019843

GO:0022627

GO:0032991

GO:0034641

GO:0034655

GO:0043226

GO:0044403

GO:0045202

GO:0070062

ILMN_1753534

ILMN_3246360

PH_hs_0029574

TC06000417.hg

TC06002737.hg

TC6_cox_hap2000107.hg

TC6_dbb_hap3000099.hg

TC6_mcf_hap5000092.hg

TC6_qbl_hap6000098.hg

TC6_ssto_hap7000088.hg

X69150_at

g11968181_3p_a_at

Participant Of

hasComponent

18SE pre-40S particle [nucleoplasm]

Other forms of this molecule

RPS18 [cytosol]

Inferred To

RPS18A [nucleoplasm] (Saccharomyces cerevisiae)

RPS18 [nucleoplasm] (Canis familiaris)

RPS18 [nucleoplasm] (Plasmodium falciparum)

RPS18 [nucleoplasm] (Sus scrofa)

rps1802 [nucleoplasm] (Schizosaccharomyces pombe)

rps-18 [nucleoplasm] (Caenorhabditis elegans)

RpS18 [nucleoplasm] (Drosophila melanogaster)

Homologues of RPS18 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of RPS18 [nucleoplasm] (Schizosaccharomyces pombe)

rps1801 [nucleoplasm] (Schizosaccharomyces pombe)

Rps18 [nucleoplasm] (Mus musculus)

Rps18 [nucleoplasm] (Rattus norvegicus)

sema4b [nucleoplasm] (Xenopus tropicalis)

RPS18B [nucleoplasm] (Saccharomyces cerevisiae)

rps18 [nucleoplasm] (Danio rerio)

rps18 [nucleoplasm] (Dictyostelium discoideum)

Cross References

RefSeq

NP_072045.1

Target Pathogen

5b354852be737e166372eb2e

OpenTargets

ENSG00000231500

GeneCards

P62269

HPA

ENSG00000231500-RPS18

Ensembl

ENSG00000231500, ENSP00000416110, ENSG00000226225, ENST00000211372, ENST00000457341, ENST00000454021, ENSG00000096150, ENSP00000403175, ENSP00000393241, ENSP00000412583, ENST00000434122, ENSG00000235650, ENST00000439602, ENSG00000223367, ENSP00000211372

PRO

P62269

PDB

5OA3, 6IP5, 6OLG, 6IP6, 5VYC, 5T2C, 6G4S, 5LKS, 6G5I, 6OLI, 6Y0G, 4V6X, 6IP8, 6G18, 6G4W, 6OM0, 6Y2L, 6G51, 5FLX, 5A2Q, 6OLZ, 6G53, 6EK0, 6QZP, 6OM7, 6Y57, 6ZOJ, 4UG0, 6OLE, 5AJ0, 6G5H, 6FEC, 6OLF, 6ZOL

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.59	3
UniProt:Q99558 MAP3K14	5	MAP3K14 [cytosol] (R-HSA-168189) Active NIK [cytosol] (R-HSA-5607646) p-MAP3K14 [cytosol] (R-HSA-168187) K48polyUb-NIK [cytosol] (R-HSA-5668525) p-T559-MAP3K14 [cytosol] (R-HSA-5668531)	0.564	2
UniProt:P03372 ESR1	8	SUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) Me260-ESR1 [cytosol] (R-HSA-9632177) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.527	2

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