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RPS3 [nucleoplasm]
Stable Identifier
R-HSA-6798714
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
40S small ribosomal protein 3, P23396, 40S ribosomal protein S3
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
RPS3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P23396 RPS3
Gene Names
RPS3, OK/SW-cl.26
Chain
initiator methionine:1, chain:2-243
Reference Genes
BioGPS Gene:6188 RPS3
COSMIC (genes):RPS3 RPS3
CTD Gene:6188 RPS3
dbSNP Gene:6188 RPS3
ENSEMBL:ENSG00000149273 RPS3
HGNC:10420 RPS3
KEGG Gene (Homo sapiens):6188 RPS3
Monarch:6188 RPS3
NCBI Gene:6188 RPS3
OMIM:600454 RPS3
UCSC:P23396 RPS3
Reference Transcript
RefSeq:NM_001256802.1 RPS3
RefSeq:NM_001005.4 RPS3
RefSeq:NM_001260507.1 RPS3
RefSeq:NM_001260506.1 RPS3
Other Identifiers
0000840066
11757264_s_at
16729103
208692_at
214208_at
2940643
2940649
3340547
3340552
3340553
3340554
3340555
3340557
3340558
3340559
3340560
3340561
3340562
3340565
3340566
3340567
3340568
3340569
3340570
3340571
3340572
3340577
34645_at
6188
63493_at
7942586
A_14_P112056
A_23_P139376
A_24_P218765
GE79155
GE84158
GO:0000184
GO:0000977
GO:0002376
GO:0003674
GO:0003677
GO:0003684
GO:0003723
GO:0003729
GO:0003735
GO:0003906
GO:0004518
GO:0004520
GO:0005198
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005739
GO:0005743
GO:0005759
GO:0005783
GO:0005819
GO:0005829
GO:0005840
GO:0005844
GO:0005856
GO:0005886
GO:0005925
GO:0006259
GO:0006281
GO:0006412
GO:0006413
GO:0006417
GO:0006464
GO:0006605
GO:0006614
GO:0006810
GO:0006915
GO:0006950
GO:0006974
GO:0007010
GO:0007049
GO:0007059
GO:0007155
GO:0007165
GO:0008017
GO:0008092
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0009056
GO:0009058
GO:0010628
GO:0014069
GO:0015031
GO:0015631
GO:0015935
GO:0016020
GO:0016829
GO:0017148
GO:0019083
GO:0019843
GO:0019899
GO:0019900
GO:0019901
GO:0022607
GO:0022627
GO:0030544
GO:0031116
GO:0031334
GO:0031397
GO:0032079
GO:0032357
GO:0032358
GO:0032587
GO:0032743
GO:0032991
GO:0034614
GO:0034641
GO:0034655
GO:0042104
GO:0042769
GO:0042981
GO:0043226
GO:0043507
GO:0044390
GO:0044403
GO:0044877
GO:0045202
GO:0045738
GO:0045739
GO:0050862
GO:0051018
GO:0051092
GO:0051225
GO:0051301
GO:0051536
GO:0051879
GO:0061481
GO:0065003
GO:0070062
GO:0070181
GO:0070301
GO:0071159
GO:0071356
GO:0072686
GO:0097100
GO:0140078
GO:1901224
GO:1902231
GO:1902546
GO:1905053
GO:1990904
GO:2001235
GO:2001272
Hs.59728.0.A1_3p_at
TC11000806.hg
X55715_at
g555940_3p_at
Participant Of
hasComponent
18SE pre-40S particle [nucleoplasm]
Other forms of this molecule
RPS3 [cytosol]
Inferred To
Homologues of RPS3 [nucleoplasm] (Sus scrofa)
RpS3 [nucleoplasm] (Drosophila melanogaster)
RPS3 [nucleoplasm] (Canis familiaris)
RPS3 [nucleoplasm] (Plasmodium falciparum)
RPS3 [nucleoplasm] (Saccharomyces cerevisiae)
RPS3 [nucleoplasm] (Sus scrofa)
rps3 [nucleoplasm] (Danio rerio)
rps3 [nucleoplasm] (Dictyostelium discoideum)
rps3 [nucleoplasm] (Schizosaccharomyces pombe)
rps3 [nucleoplasm] (Xenopus tropicalis)
Rps3 [nucleoplasm] (Mus musculus)
Rps3 [nucleoplasm] (Rattus norvegicus)
rps-3 [nucleoplasm] (Caenorhabditis elegans)
Cross References
RefSeq
NP_001247436.1
,
NP_001247435.1
,
NP_001243731.1
,
NP_000996.2
Target Pathogen
5b354852be737e166372e901
OpenTargets
ENSG00000149273
GeneCards
P23396
HPA
ENSG00000149273-RPS3
Ensembl
ENSP00000433821
,
ENST00000527446
,
ENSG00000149273
,
ENST00000531188
,
ENSP00000278572
,
ENST00000278572
,
ENSP00000434643
,
ENSP00000436971
,
ENST00000524851
PRO
P23396
PDB
1WH9
,
6Y0G
,
5OA3
,
6FEC
,
6IP8
,
6OM0
,
6Y2L
,
6G51
,
6G5I
,
6G5H
,
5AJ0
,
6OLG
,
6IP5
,
4UG0
,
6IP6
,
6OLI
,
6OLE
,
6ZOL
,
6EK0
,
5FLX
,
5A2Q
,
6OLF
,
5VYC
,
5LKS
,
5T2C
,
6QZP
,
6OLZ
,
6G53
,
4V6X
,
6ZOJ
,
6OM7
,
6Y57
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q04206 RELA
6
MeK310-RELA [nucleoplasm]
(R-HSA-8865233)
SUMO3-K37,K122,K123-RELA [nucleoplasm]
(R-HSA-4755466)
p-S276,5xAcK-RELA [nucleoplasm]
(R-HSA-5660642)
p-S276-RELA [nucleoplasm]
(R-HSA-5624468)
RELA [nucleoplasm]
(R-HSA-177676)
RELA [cytosol]
(R-HSA-168172)
0.797
8
UniProt:Q00987 MDM2
11
SUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
MDM2 [plasma membrane]
(R-HSA-416843)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [cytosol]
(R-HSA-198644)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
0.696
8
UniProt:P25963 NFKBIA
10
SUMO1-K21-NFKBIA [nucleoplasm]
(R-HSA-4656935)
PolyUb-NFKBIA [cytosol]
(R-HSA-6782960)
p-S32,S36-NFKBIA [cytosol]
(R-HSA-177677)
K48PolyUb-K21,22-p-S32,S36-IkBA [cytosol]
(R-HSA-5607659)
NFKBIA [cytosol]
(R-HSA-168151)
Ub-21,22-p-S32,S36-NFKBIA [cytosol]
(R-HSA-1168581)
NFKBIA S32I [cytosol]
(R-HSA-5228846)
NFKBIA F2_M37del [cytosol]
(R-HSA-9630119)
NFKBIA M37K [cytosol]
(R-HSA-5228805)
NFKBIA [nucleoplasm]
(R-HSA-4656929)
0.677
6
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.642
4
UniProt:P04637 TP53
27
TP53 [cytosol]
(R-HSA-8869337)
Unfolded TP53 [cytosol]
(R-HSA-6813797)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
SUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
Me2K-370,382-TP53 [nucleoplasm]
(R-HSA-3222242)
p-S15,S33,S46-TP53 [nucleoplasm]
(R-HSA-6805268)
p-S15,S392-TP53 [nucleoplasm]
(R-HSA-3222015)
p-T55-TP53 [nucleoplasm]
(R-HSA-6805400)
p-S15,S20,S392-TP53 [nucleoplasm]
(R-HSA-6805053)
p-S15,S20,S269,T284-TP53 [nucleoplasm]
(R-HSA-6805133)
p-S315-TP53 [nucleoplasm]
(R-HSA-6805106)
Ac-K120,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805656)
Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805631)
Ac-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-5628868)
Me2-K373-TP53 [nucleoplasm]
(R-HSA-6805759)
MeK-370,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222226)
p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]
(R-HSA-6804378)
Me-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222124)
Me1-K372,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805719)
p-S15,S20,S46-TP53 [nucleoplasm]
(R-HSA-6798369)
p-S37-TP53 [nucleoplasm]
(R-HSA-3239022)
PolyUb,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6804446)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6793679)
PolyUb-TP53 [cytosol]
(R-HSA-6793681)
p-S15,S20-TP53 [nucleoplasm]
(R-HSA-69683)
p-S15-TP53 [nucleoplasm]
(R-HSA-69507)
TP53 [nucleoplasm]
(R-HSA-69488)
0.632
4
UniProt:P19838 NFKB1
8
NFKB1(1-968) [extracellular region]
(R-HSA-6806304)
NFKB1(1-968) [specific granule lumen]
(R-HSA-6799557)
NFKB1(1-968) [secretory granule lumen]
(R-HSA-6801004)
NFKB1(1-433) [nucleoplasm]
(R-HSA-177655)
NFKB1(1-433) [cytosol]
(R-HSA-168168)
NFKB1(1-968) [cytosol]
(R-HSA-451607)
p-S927,S932-NFKB1(1-968) [cytosol]
(R-HSA-451611)
3xUb-p-S927,S932-NFKB1(1-968) [cytosol]
(R-HSA-451619)
0.623
5
UniProt:Q15843 NEDD8
17
C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm]
(R-HSA-8952504)
K1881-CUL9-G76-NEDD8 [cytosol]
(R-HSA-8955924)
NEDD8 [nucleoplasm]
(R-HSA-8955926)
K705-CUL4A-G76-NEDD8 [nucleoplasm]
(R-HSA-8952528)
K859-CUL4B-G76-NEDD8 [nucleoplasm]
(R-HSA-8952538)
NEDD8(77-88) [cytosol]
(R-HSA-6782654)
NEDD8(1-88) [cytosol]
(R-HSA-5690794)
C237-UBA3-G76-NEDD8 [cytosol]
(R-HSA-8951647)
C116-AcM-UBE2F-G76-NEDD8 [cytosol]
(R-HSA-8951739)
K720-CUL1-G76-NEDD8 [cytosol]
(R-HSA-8952534)
K712-CUL3-G76-NEDD8 [cytosol]
(R-HSA-8952531)
K689-CUL2-G76-NEDD8 [cytosol]
(R-HSA-8952526)
K724-CUL5-G76-NEDD8 [cytosol]
(R-HSA-8952018)
NEDD8 [cytosol]
(R-HSA-416969)
K567-TGFBR2-G76-NEDD8 [cytosol]
(R-HSA-4419906)
K556-TGFBR2-G76-NEDD8 [cytosol]
(R-HSA-4419907)
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(R-HSA-4419895)
0.623
3
UniProt:O14920 IKBKB
3
p-S177,S181-IKBKB [cytosol]
(R-HSA-202506)
IKBKB Q432Pfs*62 [cytosol]
(R-HSA-9628518)
IKBKB [cytosol]
(R-HSA-168114)
0.602
4
UniProt:P63104 YWHAZ
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.564
2
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:Q96GA3 LTV1
2
LTV1 [nucleoplasm]
(R-HSA-6791566)
LTV1 [cytosol]
(R-HSA-6791520)
0.556
3
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