Reactome | RPS17 [nucleoplasm]

RPS17 [nucleoplasm]

Stable Identifier

R-HSA-6798719

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S small ribosomal protein 17, P08708, 40S ribosomal protein S17

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P08708 RPS17

Gene Names

RPS17, RPS17L

Chain

initiator methionine:, chain:2-135

Reference Genes

BioGPS Gene:6218 RPS17

COSMIC (genes):RPS17 RPS17

CTD Gene:6218 RPS17

dbSNP Gene:6218 RPS17

ENSEMBL:ENSG00000182774 RPS17

HGNC:10397 RPS17

KEGG:hsa:6218 RPS17

Monarch:6218 RPS17

NCBI Gene:6218 RPS17

OMIM:180472 RPS17

UCSC:P08708 RPS17

Reference Transcript

RefSeq:NM_001021.4 RPS17

Other Identifiers

11744334_x_at

11744601_x_at

16812527

16812581

201665_3p_x_at

201665_PM_x_at

201665_x_at

211487_3p_x_at

211487_PM_x_at

211487_x_at

212578_3p_x_at

212578_PM_x_at

212578_x_at

2756364

2756365

2956753

34592_at

34593_g_at

3635930

3635931

3635932

3635933

3635934

3635935

3635936

3635937

3635938

3635939

3635940

3635941

3635942

3635943

3636148

3636149

3636150

3636151

3636152

3636153

3636154

3636155

3636156

3636157

3636158

3636159

3636160

3636161

3636162

6218

7990916

7990965

A_23_P117721

GE61250

GO:0002181

GO:0002376

GO:0003723

GO:0003735

GO:0005198

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006364

GO:0006412

GO:0006413

GO:0016020

GO:0022626

GO:0022627

GO:0032040

GO:0034101

GO:0042274

GO:0043226

GO:0045202

GO:1990904

HMNXSV003050899

Hs.5174.2.S1_3p_s_at

Hs.5174.2.S1_3p_x_at

ILMN_2207533

ILMN_2207539

M18000_at

PH_hs_0030178

TC15001743.hg

TC15001754.hg

g13436139_3p_s_at

g4506692_3p_a_at

g4506692_3p_s_at

g4506692_3p_x_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

Other forms of this molecule

RPS17 [cytosol]

Inferred To

RpS17 [nucleoplasm] (Drosophila melanogaster)

rps1701 [nucleoplasm] (Schizosaccharomyces pombe)

Rps17 [nucleoplasm] (Mus musculus)

Rps17 [nucleoplasm] (Rattus norvegicus)

rps-17 [nucleoplasm] (Caenorhabditis elegans)

Homologues of RPS17 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of RPS17 [nucleoplasm] (Schizosaccharomyces pombe)

RPS17B [nucleoplasm] (Saccharomyces cerevisiae)

rps17 [nucleoplasm] (Dictyostelium discoideum)

rps17 [nucleoplasm] (Xenopus tropicalis)

rps1702 [nucleoplasm] (Schizosaccharomyces pombe)

RPS17 [nucleoplasm] (Bos taurus)

RPS17 [nucleoplasm] (Canis familiaris)

RPS17 [nucleoplasm] (Danio rerio)

RPS17 [nucleoplasm] (Gallus gallus)

RPS17 [nucleoplasm] (Plasmodium falciparum)

RPS17 [nucleoplasm] (Sus scrofa)

RPS17A [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_001012.1

OpenTargets

ENSG00000182774

ENSEMBL

ENSP00000483755, ENST00000617731, ENSP00000498019, ENST00000647841

HPA

ENSG00000182774-RPS17

PRO

P08708

Pharos - Targets

P08708

Orphanet

RPS17

GlyGen

P08708

PDB

7XNY, 6ZOJ, 7QVP, 7WTZ, 6ZVJ, 8G6J, 5VYC, 8T4S, 7WTW, 6ZUO, 5AJ0, 5T2C, 4V6X, 8JDM, 6IP5, 5A2Q, 8OZ0, 6ZOL, 8XXN, 7WU0, 8XXL, 6YBS, 6ZXE, 6Z6N, 7MQA, 6G4W, 6G53, 8IFD, 6ZMO, 7QP7, 6ZMI, 6G18, 7XNX, 6ZXG, 6G5H, 7R4X, 6QZP, 8JDL, 8G61, 6OLE, 6IP6, 6YBD, 6YBW, 6ZM7, 6XA1, 8PPL, 8Y0X, 6OM0, 6ZP4, 6ZME, 6Y57, 7WTX, 6ZVH, 7QP6, 7K5I, 5LKS, 7WTV, 6OLZ, 6Z6L, 6ZN5, 6G4S, 7WTU, 6G51, 7TQL, 6G5I, 8GLP, 6ZXH, 6OLF, 8JDK, 8G60, 7A09, 6FEC, 8G5Z, 5FLX, 8XXM, 6ZON, 7MQ9, 6ZV6, 6ZMW, 6Y0G, 8G5Y, 7WTT, 8QOI, 6OM7, 4UG0, 8IFE, 6Z6M, 6ZMT, 7MQ8, 6ZXF, 5OA3, 8JDJ, 8PPK, 8Y0W, 6OLG, 6IP8, 6ZLW, 6ZOK, 6OLI, 6Y2L, 6ZXD

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.607	3
UniProt:P15880 RPS2	3	RPS2 [cytosol] (R-HSA-72347) Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [nucleoplasm] (R-HSA-6790655)	0.527	3
UniProt:P62280 RPS11	2	RPS11 [cytosol] (R-HSA-72327) RPS11 [nucleoplasm] (R-HSA-6791212)	0.527	2
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) N [cytosol] (R-COV-9694300) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [plasma membrane] (R-COV-9694356) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325)	0.527	3
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	12

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