Exocytosis of secretory granule membrane proteins

Stable Identifier
R-HSA-6798743
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Secretory vesicles provide a reservoir of membrane-associated receptors that are required at the earliest stages of the neutrophil-mediated inflammatory response. They are mobilized in response to a wide variety of inflammatory stimuli (Sengelov et al. 1993a,b). Resultant cell surface changes allow the neutrophil to establish firm contact with activated vascular epithelium (Faurschou & Borregaard 2003).

Participants
Participant Of
Orthologous Events