Exocytosis of secretory granule membrane proteins

Stable Identifier
R-HSA-6798743
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, secretory granule membrane
ReviewStatus
5/5
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Exocytosis of secretory granule membrane proteins
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Secretory vesicles provide a reservoir of membrane-associated receptors that are required at the earliest stages of the neutrophil-mediated inflammatory response. They are mobilized in response to a wide variety of inflammatory stimuli (Sengelov et al. 1993a,b). Resultant cell surface changes allow the neutrophil to establish firm contact with activated vascular epithelium (Faurschou & Borregaard 2003).
Literature References
PubMed ID Title Journal Year
23650620 Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors

Heegaard, NH, Rørvig, S, Borregaard, N, Østergaard, O

J. Leukoc. Biol. 2013
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Orthologous Events
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Authored
Jupe, S  (2015-09-21)
Reviewed
Heegaard, N  (2016-06-13)
Created
Jupe, S  (2015-09-21)
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