Reactome | CAP1 [azurophil granule lumen]

CAP1 [azurophil granule lumen]

Stable Identifier

R-HSA-6798752

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

azurophil granule lumen

Synonyms

Adenylyl cyclase-associated protein 1

Icon

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q01518 CAP1

Gene Names

CAP1, CAP

Chain

initiator methionine:, chain:2-475

Reference Genes

BioGPS Gene:10487 CAP1

COSMIC (genes):CAP1 CAP1

CTD Gene:10487 CAP1

dbSNP Gene:10487 CAP1

ENSEMBL:ENSG00000131236 CAP1

HGNC:20040 CAP1

KEGG:hsa:10487 CAP1

Monarch:10487 CAP1

NCBI Gene:10487 CAP1

OMIM:617801 CAP1

UCSC:Q01518 CAP1

Reference Transcript

Other Identifiers

10487

11719377_x_at

11745801_s_at

16662968

200625_PM_s_at

200625_s_at

213798_PM_s_at

213798_s_at

2331728

2331729

2331730

2331732

2331736

2331737

2331738

2331739

2331740

2331741

2331742

2331743

2331744

2331745

2331746

2331747

2331748

2331749

2331750

2331751

2331752

2331753

2331754

2331755

2331757

2331758

2331760

2630486

2630488

2630494

3286367

3286369

7900382

935_at

A_14_P104430

A_24_P62615

A_33_P3281816

GE61261

GE742012

GO:0000902

GO:0001667

GO:0003779

GO:0005515

GO:0005576

GO:0005737

GO:0005856

GO:0005886

GO:0005925

GO:0006898

GO:0007010

GO:0007015

GO:0007163

GO:0007165

GO:0007190

GO:0008092

GO:0008179

GO:0016192

GO:0019933

GO:0030036

GO:0030864

GO:0034330

GO:0035578

GO:0043226

GO:0048870

GO:0070062

GO:0098793

GO:0098794

GO:0098885

GO:0098978

HMNXSV003021654

Hs.104125.2.A1_3p_a_at

ILMN_1797604

ILMN_1880116

L12168_at

PH_hs_0005778

TC01000504.hg

g10938021_3p_a_at

Participates

as a member of

Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)

Other forms of this molecule

CAP1 [extracellular region]

CAP1 [cytosol]

Inferred To

cap1 [azurophil granule lumen] (Danio rerio)

cap1 [azurophil granule lumen] (Schizosaccharomyces pombe)

cap1 [azurophil granule lumen] (Xenopus tropicalis)

cas-1 [azurophil granule lumen] (Caenorhabditis elegans)

SRV2 [azurophil granule lumen] (Saccharomyces cerevisiae)

capt [azurophil granule lumen] (Drosophila melanogaster)

cap [azurophil granule lumen] (Dictyostelium discoideum)

Cap1 [azurophil granule lumen] (Mus musculus)

Cap1 [azurophil granule lumen] (Rattus norvegicus)

CAP1 [azurophil granule lumen] (Bos taurus)

CAP1 [azurophil granule lumen] (Canis familiaris)

CAP1 [azurophil granule lumen] (Gallus gallus)

CAP1 [azurophil granule lumen] (Sus scrofa)

Cross References

OpenTargets

ENSG00000131236

ENSEMBL

ENST00000372797, ENST00000340450, ENSP00000361884, ENST00000372802, ENST00000372798, ENSP00000361883, ENST00000372805, ENSP00000361891, ENSP00000344832, ENSP00000361888, ENST00000372792, ENSP00000361878

HPA

ENSG00000131236-CAP1

PRO

Q01518

Pharos - Targets

Q01518

GlyGen

Q01518

PDB

1K8F

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.725	14
UniProt:P0DTC3 3a	9	O-glycosyl 3a [virion membrane] (R-COV-9694395) O-glycosyl 3a [endocytic vesicle membrane] (R-COV-9694729) O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694386) GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694658) 3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694716) 3a [endoplasmic reticulum lumen] (R-COV-9694584) O-glycosyl 3a [endolysosome membrane] (R-COV-9754541) O-glycosyl 3a [plasma membrane] (R-COV-9694433) O-glycosyl 3a [extracellular region] (R-COV-9694387)	0.613	3
UniProt:P60709 ACTB	5	ACTB [plasma membrane] (R-HSA-196016) ACTB [lysosomal membrane] (R-HSA-196160) ACTB [cytosol] (R-HSA-201861) ACTB [nucleoplasm] (R-HSA-3321990) Unfolded ACTB [cytosol] (R-HSA-390462)	0.527	4

Cite Us!