Reactome | GLB1 [azurophil granule lumen]

GLB1 [azurophil granule lumen]

Stable Identifier

R-HSA-6799124

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

azurophil granule lumen

Synonyms

Beta-galactosidase, BGAL_HUMAN

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External Reference Information

External Reference

UniProt:P16278 GLB1

Gene Names

GLB1, ELNR1

Chain

signal peptide:1-23, propeptide:24-28, chain:29-677

Reference Genes

BioGPS Gene:2720 GLB1

COSMIC (genes):GLB1 GLB1

CTD Gene:2720 GLB1

dbSNP Gene:2720 GLB1

ENSEMBL:ENSG00000170266 GLB1

HGNC:4298 GLB1

KEGG:hsa:2720 GLB1

Monarch:2720 GLB1

NCBI Gene:2720 GLB1

OMIM:611458 GLB1

UCSC:P16278 GLB1

Reference Transcript

Other Identifiers

11715657_a_at

11729661_a_at

11729662_x_at

201576_PM_s_at

201576_s_at

2668206

2668207

2668208

2668209

2668210

2668221

2668222

2668223

2668224

2668226

2668228

2668229

2668230

2668231

2668234

2668236

2668237

2668238

2668239

2668240

2668241

2668242

2668243

2668244

2668245

2668250

2668251

2668252

2668253

2668255

2668256

2668257

2668258

2668259

2668262

2668265

2668266

2668281

2668282

2668283

2720

37742_at

8086028

A_23_P61529

A_23_P61531

GE57941

GO:0003824

GO:0004553

GO:0004565

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005764

GO:0005773

GO:0005794

GO:0005975

GO:0006629

GO:0006790

GO:0016787

GO:0016798

GO:0016936

GO:0019388

GO:0030163

GO:0030200

GO:0035578

GO:0042340

GO:0042803

GO:0043202

GO:0043226

GO:0043231

GO:0046479

GO:0048471

GO:0051413

GO:0070062

GO:1901135

GO:1904016

GO:1904813

HMNXSV003034032

ILMN_1735155

ILMN_2289111

ILMN_2397721

M34423_at

PH_hs_0026028

g10834965_3p_a_at

Participates

as a member of

Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)

Other forms of this molecule

GLB1 [lysosomal lumen]

GLB1 [ficolin-1-rich granule lumen]

GLB1 [extracellular region]

GLB1 W273L [lysosomal lumen]

GLB1 R482C [lysosomal lumen]

GLB1 Y83C [lysosomal lumen]

GLB1 W509C [lysosomal lumen]

Inferred To

glb1 [azurophil granule lumen] (Dictyostelium discoideum)

bgal-1 [azurophil granule lumen] (Caenorhabditis elegans)

Ect3 [azurophil granule lumen] (Drosophila melanogaster)

glb1l [azurophil granule lumen] (Xenopus tropicalis)

bgal-2 [azurophil granule lumen] (Caenorhabditis elegans)

Glb1 [azurophil granule lumen] (Rattus norvegicus)

GLB1 [azurophil granule lumen] (Bos taurus)

GLB1 [azurophil granule lumen] (Canis familiaris)

GLB1 [azurophil granule lumen] (Gallus gallus)

GLB1 [azurophil granule lumen] (Mus musculus)

GLB1 [azurophil granule lumen] (Sus scrofa)

Homologues of GLB1 [azurophil granule lumen] (Caenorhabditis elegans)

Homologues of GLB1 [azurophil granule lumen] (Drosophila melanogaster)

Gal [azurophil granule lumen] (Drosophila melanogaster)

Cross References

RefSeq

NP_001073279.1, NP_001303969.1, NP_000395.2, NP_001129074.1

OpenTargets

ENSG00000170266

ENSEMBL

ENSP00000306920, ENSG00000170266, ENST00000307363, ENSP00000382333, ENST00000399402

ZINC - Substances

BGAL_HUMAN

ZINC target

P16278

PRO

P16278

GlyGen

P16278

PDB

3THC, 3THD, 3WEZ, 3WF4, 3WF2, 3WF3, 3WF0, 3WF1

IntEnz

3.2.1.23

HPA

ENSG00000170266-GLB1

GeneCards

GLB1

Pharos - Targets

P16278

Orphanet

GLB1

ZINC - Predictions - Purchasable

BGAL_HUMAN

HMDB Protein

HMDBP00843

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:Q9BRI3 SLC30A2	2	SLC30A2 [endosome membrane] (R-HSA-435363) SLC30A2 [synaptic vesicle membrane] (R-HSA-4084714)	0.556	3
UniProt:P61586 RHOA	6	RHOA [plasma membrane] (R-HSA-194510) RHOA [cell junction] (R-HSA-2134503) RHOA [cytosol] (R-HSA-194866) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971)	0.527	2
UniProt:P08670 VIM	11	Vimentin [lysosomal lumen] (R-HSA-9659977) Vimentin [cytosol] (R-HSA-9646687) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [late endosome lumen] (R-HSA-9660019) VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-429) [cytosol] (R-HSA-350317) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294) VIM(2-85) [cytosol] (R-HSA-350264)	0.508	2

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