The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I

Stable Identifier
R-HSA-6799196
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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In the last step, the MCIA complex and it is assumed all of the assembly factors (NDUFAF2-7, TIMMDC1) dissociate from the 980kDa complex to leave mature Complex I (Mckenzie & Ryan 2010, Andrews et al. 2013).

Literature References
PubMed ID Title Journal Year
24191001 Assembly factors for the membrane arm of human complex I

Andrews, B, Carroll, J, Ding, S, Fearnley, IM, Walker, JE

Proc. Natl. Acad. Sci. U.S.A. 2013
20552642 Assembly factors of human mitochondrial complex I and their defects in disease

McKenzie, M, Ryan, MT

IUBMB Life 2010
Participants
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Orthologous Events
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