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ACPP [azurophil granule membrane]
Stable Identifier
R-HSA-6799214
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule membrane
Synonyms
Prostatic acid phosphatase, PPAP_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule membrane proteins (Homo sapiens)
Azurophil granule membrane proteins [azurophil granule membrane] (Homo sapiens)
ACPP [azurophil granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15309 ACP3
Gene Names
ACP3, ACPP
Chain
signal peptide:1-32, chain:33-386, peptide:248-286
Reference Genes
BioGPS Gene:55 ACP3
COSMIC (genes):ACPP ACP3
CTD Gene:55 ACP3
dbSNP Gene:55 ACP3
ENSEMBL:ENSG00000014257 ACPP
HGNC:125 ACP3
KEGG:hsa:55 ACP3
Monarch:55 ACP3
NCBI Gene:55 ACP3
OMIM:171790 ACP3
UCSC:P15309 ACP3
Reference Transcript
RefSeq:NM_001292037.1 ACP3
RefSeq:NM_001099.4 ACP3
RefSeq:NM_001134194.1 ACP3
Other Identifiers
11729013_at
11739048_at
11739049_at
11739050_s_at
11748861_a_at
16945682
204393_PM_s_at
204393_s_at
237030_PM_at
237030_at
2642729
2642730
2642731
2642734
2642736
2642737
2642738
2642739
2642742
2642743
2642744
2642745
2642746
2642749
2642750
2642752
2642754
2642755
2642757
2642758
2642759
2642760
2642761
2642762
2642763
2642765
2642766
2642767
32200_at
55
617_at
8082673
80874_at
A_14_P101781
A_24_P46130
GE79467
GO:0003824
GO:0003993
GO:0004725
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005771
GO:0005773
GO:0005829
GO:0005886
GO:0006144
GO:0006629
GO:0006766
GO:0006772
GO:0006790
GO:0007040
GO:0008253
GO:0009117
GO:0012506
GO:0016020
GO:0016311
GO:0016787
GO:0016791
GO:0030141
GO:0030175
GO:0031410
GO:0031985
GO:0033265
GO:0035577
GO:0042131
GO:0042802
GO:0042803
GO:0043226
GO:0045177
GO:0046085
GO:0051930
GO:0052642
GO:0055086
GO:0060090
GO:0060168
GO:0070062
GO:0106411
GO:0140096
GO:1901135
HMNXSV003019762
HMNXSV003030812
Hs.152298.0.A1_3p_at
ILMN_1758323
M24902_at
PH_hs_0024475
TC03000714.hg
g6382063_3p_at
Participates
as a member of
Azurophil granule membrane proteins [azurophil granule membrane] (Homo sapiens)
Other forms of this molecule
ACPP [plasma membrane]
Inferred To
ACP3 [azurophil granule membrane]
(Canis familiaris)
ACP3 [azurophil granule membrane]
(Sus scrofa)
acp-5 [azurophil granule membrane]
(Caenorhabditis elegans)
pho-14 [azurophil granule membrane]
(Caenorhabditis elegans)
pho-1 [azurophil granule membrane]
(Caenorhabditis elegans)
pho-6 [azurophil granule membrane]
(Caenorhabditis elegans)
pho-10 [azurophil granule membrane]
(Caenorhabditis elegans)
acp-6 [azurophil granule membrane]
(Caenorhabditis elegans)
cf60 [azurophil granule membrane]
(Dictyostelium discoideum)
Acph-1 [azurophil granule membrane]
(Drosophila melanogaster)
Dmel\CG9452 [azurophil granule membrane]
(Drosophila melanogaster)
Homologues of ACPP [azurophil granule membrane]
(Caenorhabditis elegans)
Homologues of ACPP [azurophil granule membrane]
(Dictyostelium discoideum)
Homologues of ACPP [azurophil granule membrane]
(Drosophila melanogaster)
Homologues of ACPP [azurophil granule membrane]
(Xenopus tropicalis)
pho-5 [azurophil granule membrane]
(Caenorhabditis elegans)
Dmel\CG6656 [azurophil granule membrane]
(Drosophila melanogaster)
acp-7 [azurophil granule membrane]
(Caenorhabditis elegans)
acp3 [azurophil granule membrane]
(Xenopus tropicalis)
pho-11 [azurophil granule membrane]
(Caenorhabditis elegans)
pho-4 [azurophil granule membrane]
(Caenorhabditis elegans)
acp2 [azurophil granule membrane]
(Danio rerio)
acp2 [azurophil granule membrane]
(Xenopus tropicalis)
pho-9 [azurophil granule membrane]
(Caenorhabditis elegans)
Dmel\CG9451 [azurophil granule membrane]
(Drosophila melanogaster)
Dmel\CG9449 [azurophil granule membrane]
(Drosophila melanogaster)
pho-12 [azurophil granule membrane]
(Caenorhabditis elegans)
ACPP [azurophil granule membrane]
(Bos taurus)
ACPP [azurophil granule membrane]
(Caenorhabditis elegans)
ACPP [azurophil granule membrane]
(Dictyostelium discoideum)
ACPP [azurophil granule membrane]
(Gallus gallus)
ACPP [azurophil granule membrane]
(Mus musculus)
ACPP [azurophil granule membrane]
(Rattus norvegicus)
ACPP [azurophil granule membrane]
(Schizosaccharomyces pombe)
pho-7 [azurophil granule membrane]
(Caenorhabditis elegans)
pho-8 [azurophil granule membrane]
(Caenorhabditis elegans)
pho-13 [azurophil granule membrane]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENST00000351273
,
ENSP00000323036
,
ENSP00000417744
,
ENST00000336375
,
ENST00000475741
,
ENSP00000337471
OpenTargets
ENSG00000014257
HPA
ENSG00000014257-ACP3
ZINC - Substances
PPAP_HUMAN
ZINC target
P15309
PRO
P15309
Pharos - Targets
P15309
ZINC - Predictions - Purchasable
PPAP_HUMAN
HMDB Protein
HMDBP00098
PDB
2MG0
,
1CVI
,
2HPA
,
3PPD
,
8XJ4
,
2L79
,
2L3H
,
1ND5
,
1ND6
,
2L77
,
7ZZV
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04626 ERBB2
20
ERBB2 G309E [plasma membrane]
(R-HSA-9665342)
ERBB2 G309A [plasma membrane]
(R-HSA-9665349)
ERBB2 S310F [plasma membrane]
(R-HSA-9665350)
ERBB2 S310Y [plasma membrane]
(R-HSA-9665344)
p-6Y-ERBB2 G309A [plasma membrane]
(R-HSA-9665381)
p-6Y-ERBB2 G309E [plasma membrane]
(R-HSA-9665382)
p-6Y-ERBB2 S310F [plasma membrane]
(R-HSA-9665379)
p-6Y-ERBB2 S310Y [plasma membrane]
(R-HSA-9665385)
p-Y-ERBB2 L755P [plasma membrane]
(R-HSA-9654268)
p-Y-ERBB2 I767M [plasma membrane]
(R-HSA-9654303)
p-Y-ERBB2 T798I [plasma membrane]
(R-HSA-9654618)
p-Y-ERBB2 Y772_A775dup [plasma membrane]
(R-HSA-9665652)
p-Y-ERBB2 T862A [plasma membrane]
(R-HSA-9654695)
p-Y-ERBB2 T798M [plasma membrane]
(R-HSA-9654615)
p-Y-ERBB2 H878Y [plasma membrane]
(R-HSA-9654833)
p-Y-ERBB2 V777L [plasma membrane]
(R-HSA-9654401)
p-Y-ERBB2 L755S [plasma membrane]
(R-HSA-9654194)
p-Y-ERBB2 V777E [plasma membrane]
(R-HSA-9654397)
p-Y-ERBB2 V777M [plasma membrane]
(R-HSA-9654398)
p-Y-ERBB2 L755M [plasma membrane]
(R-HSA-9654191)
0.472
2
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