Reactome | LAMTOR1 [azurophil granule membrane]

LAMTOR1 [azurophil granule membrane]

Stable Identifier

R-HSA-6799633

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

azurophil granule membrane

Synonyms

Ragulator complex protein LAMTOR1, LTOR1_HUMAN

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External Reference Information

External Reference

UniProt:Q6IAA8 LAMTOR1

Gene Names

LAMTOR1, C11orf59, PDRO, PP7157

Chain

initiator methionine:1, chain:2-161

Reference Genes

BioGPS Gene:55004 LAMTOR1

COSMIC (genes):LAMTOR1 LAMTOR1

CTD Gene:55004 LAMTOR1

dbSNP Gene:55004 LAMTOR1

ENSEMBL:ENSG00000149357 LAMTOR1

HGNC:26068 LAMTOR1

KEGG Gene (Homo sapiens):55004 LAMTOR1

Monarch:55004 LAMTOR1

NCBI Gene:55004 LAMTOR1

OMIM:613510 LAMTOR1

UCSC:Q6IAA8 LAMTOR1

Reference Transcript

RefSeq:NM_017907.2 LAMTOR1

Other Identifiers

0000380458

11742925_a_at

11749390_x_at

11756743_x_at

223009_at

3380988

3380989

3380991

3380992

3380993

3380994

3380995

55004

56435_at

7950119

A_23_P2114

GE82246

GO:0001558

GO:0001919

GO:0002376

GO:0003674

GO:0005085

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005886

GO:0006464

GO:0006629

GO:0006810

GO:0006914

GO:0007032

GO:0007040

GO:0007049

GO:0007050

GO:0007165

GO:0008150

GO:0009056

GO:0010872

GO:0010874

GO:0016020

GO:0016192

GO:0016197

GO:0016241

GO:0019899

GO:0031410

GO:0031902

GO:0032008

GO:0032418

GO:0032991

GO:0034613

GO:0035577

GO:0035579

GO:0040007

GO:0042592

GO:0042632

GO:0043226

GO:0043312

GO:0043410

GO:0045121

GO:0051020

GO:0060090

GO:0060620

GO:0070062

GO:0071230

GO:0071986

GO:0101003

ILMN_1815878

PH_hs_0025135

PH_hs_0035941

TC11002053.hg

g12804574_3p_at

Participant Of

hasMember

Azurophil granule membrane proteins [azurophil granule membrane]

Other forms of this molecule

LAMTOR1 [ficolin-1-rich granule membrane]

LAMTOR1 [specific granule membrane]

LAMTOR1 [plasma membrane]

LAMTOR1 [lysosomal membrane]

Inferred To

Lamtor1 [azurophil granule membrane] (Mus musculus)

Lamtor1 [azurophil granule membrane] (Rattus norvegicus)

p18 [azurophil granule membrane] (Drosophila melanogaster)

LAMTOR1 [azurophil granule membrane] (Bos taurus)

LAMTOR1 [azurophil granule membrane] (Canis familiaris)

LAMTOR1 [azurophil granule membrane] (Dictyostelium discoideum)

LAMTOR1 [azurophil granule membrane] (Gallus gallus)

LAMTOR1 [azurophil granule membrane] (Sus scrofa)

lamtor1 [azurophil granule membrane] (Danio rerio)

lamtor1 [azurophil granule membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_060377.1

OpenTargets

ENSG00000149357

GeneCards

Q6IAA8

HPA

ENSG00000149357-LAMTOR1

Ensembl

ENSP00000278671, ENSG00000149357, ENST00000278671

PRO

Q6IAA8

PDB

5X6V, 6EHP, 6ULG, 6B9X, 5Y39, 5Y3A, 6NZD, 6U62, 6EHR, 5X6U

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y2Q5 LAMTOR2	5	LAMTOR2 [endosome membrane] (R-HSA-5693293) LAMTOR2 [lysosomal membrane] (R-HSA-5653583) LAMTOR2 [tertiary granule membrane] (R-HSA-6800165) LAMTOR2 [plasma membrane] (R-HSA-6806286) LAMTOR2 [specific granule membrane] (R-HSA-6800168)	0.873	16
UniProt:Q9HB90 RRAGC	1	RRAGC [cytosol] (R-HSA-5653949)	0.826	16
UniProt:O43504 LAMTOR5	1	LAMTOR5 [lysosomal membrane] (R-HSA-5655441)	0.777	9
UniProt:Q0VGL1 LAMTOR4	1	LAMTOR4 [lysosomal membrane] (R-HSA-5655432)	0.777	9
UniProt:Q7L523 RRAGA	2	RRAGA [cytosol] (R-HSA-5653577) K63polyUb-K142,K220,K230,K244-RRAGA [cytosol] (R-HSA-8938830)	0.758	11
UniProt:Q9UHA4 LAMTOR3	5	LAMTOR3 [endosome membrane] (R-HSA-5693294) LAMTOR3 [lysosomal membrane] (R-HSA-5653581) LAMTOR3 [tertiary granule membrane] (R-HSA-6800189) LAMTOR3 [plasma membrane] (R-HSA-6806307) LAMTOR3 [specific granule membrane] (R-HSA-6800178)	0.748	7
UniProt:Q5VZM2 RRAGB	1	RRAGB [cytosol] (R-HSA-5653579)	0.725	6
UniProt:Q8NBW4 SLC38A9	1	SLC38A9 [lysosomal membrane] (R-HSA-5215938)	0.702	12
UniProt:Q9NQL2 RRAGD	1	RRAGD [cytosol] (R-HSA-5653953)	0.643	3
UniProt:P78358 CTG1B			0.556	3
UniProt:Q8N122 RPTOR	3	RPTOR [cytosol] (R-HSA-3006727) p-S722,S792-RPTOR [cytosol] (R-HSA-3132767) RPTOR [nucleoplasm] (R-HSA-5083664)	0.527	2

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