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VAMP8 [azurophil granule membrane]
Stable Identifier
R-HSA-6799703
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule membrane
Synonyms
Vesicle-associated membrane protein 8, VAMP8_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule membrane proteins (Homo sapiens)
Azurophil granule membrane proteins [azurophil granule membrane] (Homo sapiens)
VAMP8 [azurophil granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BV40 VAMP8
Gene Names
VAMP8
Chain
chain:1-100
Reference Genes
BioGPS Gene:8673 VAMP8
COSMIC (genes):VAMP8 VAMP8
CTD Gene:8673 VAMP8
dbSNP Gene:8673 VAMP8
ENSEMBL:ENSG00000118640 VAMP8
HGNC:12647 VAMP8
KEGG:hsa:8673 VAMP8
Monarch:8673 VAMP8
NCBI Gene:8673 VAMP8
OMIM:603177 VAMP8
UCSC:Q9BV40 VAMP8
Reference Transcript
RefSeq:NM_003761.4 VAMP8
Other Identifiers
11717012_s_at
16882277
202546_PM_at
202546_at
2491662
2491663
2491667
2491668
2491669
2491670
2491671
2491672
2491673
2491675
32715_at
49686_s_at
8043197
8673
A_14_P129859
A_23_P28434
GE61583
GO:0005484
GO:0005515
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005769
GO:0005773
GO:0005829
GO:0005886
GO:0006906
GO:0006914
GO:0015031
GO:0016020
GO:0016192
GO:0016240
GO:0019869
GO:0019905
GO:0030667
GO:0030669
GO:0030670
GO:0031201
GO:0031410
GO:0031901
GO:0031902
GO:0031982
GO:0035493
GO:0035577
GO:0035579
GO:0042589
GO:0043226
GO:0046718
GO:0048471
GO:0051607
GO:0055037
GO:0055038
GO:0060090
GO:0061024
GO:0065003
GO:0070062
GO:0070254
GO:0070821
GO:0097352
GO:0098542
GO:0098594
GO:0098772
GO:1903076
GO:1903531
GO:1903595
HMNXSV003027198
ILMN_2190084
PH_hs_0010333
TC02000512.hg
g4507864_3p_at
Participates
as a member of
Azurophil granule membrane proteins [azurophil granule membrane] (Homo sapiens)
Other forms of this molecule
VAMP8 [clathrin-coated endocytic vesicle membrane]
VAMP8 [secretory granule membrane]
VAMP8 [cytoplasmic vesicle membrane]
VAMP8 [Golgi membrane]
VAMP8 [lysosomal membrane]
VAMP8 [phagocytic vesicle membrane]
VAMP8 [recycling endosome membrane]
VAMP8 [tertiary granule membrane]
VAMP8 [specific granule membrane]
VAMP8 [plasma membrane]
Inferred To
snb-1 [azurophil granule membrane]
(Caenorhabditis elegans)
sybA [azurophil granule membrane]
(Dictyostelium discoideum)
snb-6 [azurophil granule membrane]
(Caenorhabditis elegans)
snb-5 [azurophil granule membrane]
(Caenorhabditis elegans)
sybB [azurophil granule membrane]
(Dictyostelium discoideum)
VAMP8 [azurophil granule membrane]
(Bos taurus)
VAMP8 [azurophil granule membrane]
(Canis familiaris)
VAMP8 [azurophil granule membrane]
(Drosophila melanogaster)
VAMP8 [azurophil granule membrane]
(Sus scrofa)
Syb [azurophil granule membrane]
(Drosophila melanogaster)
snb-2 [azurophil granule membrane]
(Caenorhabditis elegans)
vamp-7 [azurophil granule membrane]
(Caenorhabditis elegans)
snb-7 [azurophil granule membrane]
(Caenorhabditis elegans)
Vamp8 [azurophil granule membrane]
(Mus musculus)
Vamp8 [azurophil granule membrane]
(Rattus norvegicus)
Homologues of VAMP8 [azurophil granule membrane]
(Caenorhabditis elegans)
Homologues of VAMP8 [azurophil granule membrane]
(Dictyostelium discoideum)
Homologues of VAMP8 [azurophil granule membrane]
(Drosophila melanogaster)
vamp8 [azurophil granule membrane]
(Danio rerio)
vamp8 [azurophil granule membrane]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000263864
,
ENST00000263864
OpenTargets
ENSG00000118640
HPA
ENSG00000118640-VAMP8
PRO
Q9BV40
Pharos - Targets
Q9BV40
PDB
7BV6
,
4WY4
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95721 SNAP29
3
SNAP29 [azurophil granule membrane]
(R-HSA-6799359)
SNAP29 [plasma membrane]
(R-HSA-2029020)
SNAP29 [Golgi membrane]
(R-HSA-6810997)
0.832
8
UniProt:P56962 STX17
1
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-6807769)
0.737
11
UniProt:O15400 STX7
0.669
5
UniProt:Q9UNK0 STX8
0.643
5
UniProt:Q86Y82 STX12
0.643
5
UniProt:O43752 STX6
2
STX6 [trans-Golgi network membrane]
(R-HSA-6811007)
STX6 [Golgi membrane]
(R-HSA-6811004)
0.643
4
UniProt:O75558 STX11
0.527
3
UniProt:Q8N4C7 STX19
0.527
2
UniProt:Q13503 MED21
1
MED21 [nucleoplasm]
(R-HSA-212456)
0.527
2
UniProt:O88384
2
Vti1b [extracellular region]
(R-MMU-8862983)
Vti1b [platelet alpha granule lumen]
(R-MMU-8862964)
0.527
3
UniProt:Q9P2W9 STX18
1
STX18 [endoplasmic reticulum membrane]
(R-HSA-2029079)
0.527
3
UniProt:P54920 NAPA
1
NAPA [cytosol]
(R-HSA-264469)
0.527
2
UniProt:O15155 BET1
3
BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688142)
BET1 [transport vesicle]
(R-HSA-6808719)
BET1 [Golgi membrane]
(R-HSA-6807743)
0.527
2
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