Exocytosis of ficolin-rich granule membrane proteins

Stable Identifier
R-HSA-6800426
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ficolin-1-rich granule membrane, plasma membrane
ReviewStatus
5/5
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Exocytosis of ficolin-rich granule membrane proteins
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Ficoli-1 rich granules are a relatively new fourth neutrophil granule population that is enriched in the microbial lectin ficolin-1. Ficolin-1 is present in tertiary granules, but ficolin-1 rich granules can be differentiated by having low levels of gelatinases and an elevated exocytosis propensity (Rorvig et al. 2009, 2013). The importance of these granules may be to provide rapid release of pattern recognition molecules to activate the lectin complement pathway (Rorvig et al. 2009).
Literature References
PubMed ID Title Journal Year
23650620 Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors

Heegaard, NH, Rørvig, S, Borregaard, N, Østergaard, O

J. Leukoc. Biol. 2013
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Orthologous Events
Exocytosis of ficolin-rich granule membrane proteins (Bos taurus)
Exocytosis of ficolin-rich granule membrane proteins (Caenorhabditis elegans)
Exocytosis of ficolin-rich granule membrane proteins (Canis familiaris)
Exocytosis of ficolin-rich granule membrane proteins (Danio rerio)
Exocytosis of ficolin-rich granule membrane proteins (Dictyostelium discoideum)
Exocytosis of ficolin-rich granule membrane proteins (Drosophila melanogaster)
Exocytosis of ficolin-rich granule membrane proteins (Gallus gallus)
Exocytosis of ficolin-rich granule membrane proteins (Mus musculus)
Exocytosis of ficolin-rich granule membrane proteins (Plasmodium falciparum)
Exocytosis of ficolin-rich granule membrane proteins (Rattus norvegicus)
Exocytosis of ficolin-rich granule membrane proteins (Saccharomyces cerevisiae)
Exocytosis of ficolin-rich granule membrane proteins (Schizosaccharomyces pombe)
Exocytosis of ficolin-rich granule membrane proteins (Sus scrofa)
Exocytosis of ficolin-rich granule membrane proteins (Xenopus tropicalis)
Authored
Jupe, S  (2015-09-21)
Reviewed
Heegaard, N  (2016-06-13)
Created
Jupe, S  (2015-09-29)
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