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PSMD3 [secretory granule lumen]
Stable Identifier
R-HSA-6800873
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule lumen
Synonyms
26S proteasome non-ATPase regulatory subunit 3, 26S proteasome regulatory subunit S3, Proteasome subunit p58
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
PSMD3 [secretory granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43242 PSMD3
Gene Names
PSMD3
Chain
chain:1-534
Reference Genes
BioGPS Gene:5709 PSMD3
COSMIC (genes):PSMD3 PSMD3
CTD Gene:5709 PSMD3
dbSNP Gene:5709 PSMD3
ENSEMBL:ENSG00000108344 PSMD3
HGNC:9560 PSMD3
KEGG Gene (Homo sapiens):5709 PSMD3
Monarch:5709 PSMD3
NCBI Gene:5709 PSMD3
OMIM:617676 PSMD3
UCSC:O43242 PSMD3
Reference Transcript
RefSeq:NM_002809.3 PSMD3
Other Identifiers
0003130746
11715515_a_at
11715516_x_at
11749048_a_at
16833934
201388_at
3720637
3720638
3720639
3720640
3720646
3720647
3720649
3720650
3720651
3720653
3720659
3720660
3720662
3720663
3720665
3720670
3720672
3720673
3720674
39155_at
5709
8006984
A_23_P26783
A_24_P289726
GE81195
GO:0000165
GO:0000209
GO:0000278
GO:0000502
GO:0002223
GO:0002376
GO:0002479
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005838
GO:0006464
GO:0006511
GO:0006520
GO:0006521
GO:0006810
GO:0006950
GO:0007049
GO:0007165
GO:0007267
GO:0008150
GO:0008541
GO:0009056
GO:0009058
GO:0010972
GO:0016020
GO:0016192
GO:0016579
GO:0022624
GO:0030154
GO:0030234
GO:0031145
GO:0031146
GO:0031410
GO:0032991
GO:0033209
GO:0034641
GO:0034655
GO:0034774
GO:0038061
GO:0038095
GO:0042176
GO:0043161
GO:0043226
GO:0043312
GO:0043488
GO:0043687
GO:0044281
GO:0048856
GO:0050790
GO:0050852
GO:0055085
GO:0060071
GO:0061418
GO:0070062
GO:0070498
GO:0090090
GO:0090263
GO:1901990
GO:1902036
GO:1904813
HMNXSV003001923
ILMN_1796430
PH_hs_0001007
TC17000485.hg
g4506228_3p_s_at
Participates
as a member of
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
Other forms of this molecule
PSMD3 [ficolin-1-rich granule lumen]
PSMD3 [extracellular region]
PSMD3 [nucleoplasm]
PSMD3 [cytosol]
Inferred To
Rpn3 [secretory granule lumen]
(Drosophila melanogaster)
rpn-3 [secretory granule lumen]
(Caenorhabditis elegans)
Psmd3 [secretory granule lumen]
(Mus musculus)
Psmd3 [secretory granule lumen]
(Rattus norvegicus)
RPN3 [secretory granule lumen]
(Saccharomyces cerevisiae)
psmD3 [secretory granule lumen]
(Dictyostelium discoideum)
psmd3 [secretory granule lumen]
(Danio rerio)
psmd3 [secretory granule lumen]
(Xenopus tropicalis)
rpn3 [secretory granule lumen]
(Schizosaccharomyces pombe)
PSMD3 [secretory granule lumen]
(Bos taurus)
PSMD3 [secretory granule lumen]
(Canis familiaris)
PSMD3 [secretory granule lumen]
(Gallus gallus)
PSMD3 [secretory granule lumen]
(Plasmodium falciparum)
PSMD3 [secretory granule lumen]
(Sus scrofa)
Cross References
RefSeq
NP_002800.2
Target Pathogen
5b354852be737e166372eb3a
OpenTargets
ENSG00000108344
HPA
ENSG00000108344-PSMD3
GeneCards
O43242
Ensembl
ENSG00000108344
,
ENST00000264639
,
ENSP00000264639
PRO
O43242
PDB
6MSB
,
5VFU
,
5GJQ
,
5VHF
,
5VFT
,
5M32
,
5T0C
,
5LN3
,
5VHI
,
6MSK
,
6MSD
,
5T0H
,
6WJN
,
5VHH
,
5GJR
,
5T0G
,
6MSH
,
5VFQ
,
6MSG
,
5T0J
,
6WJD
,
5VFP
,
5T0I
,
6MSJ
,
6MSE
,
5VFS
,
5VGZ
,
5VFR
,
5VHS
,
5L4K
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y5K5 UCHL5
2
UCHL5 [nucleoplasm]
(R-HSA-5689584)
UCHL5 [cytosol]
(R-HSA-1629778)
0.669
4
UniProt:O00487 PSMD14
5
PSMD14 [extracellular region]
(R-HSA-6806511)
PSMD14 [ficolin-1-rich granule lumen]
(R-HSA-6800419)
PSMD14 [secretory granule lumen]
(R-HSA-6800926)
PSMD14 [nucleoplasm]
(R-HSA-174329)
PSMD14 [cytosol]
(R-HSA-68722)
0.564
2
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:P25963 NFKBIA
10
SUMO1-K21-NFKBIA [nucleoplasm]
(R-HSA-4656935)
PolyUb-NFKBIA [cytosol]
(R-HSA-6782960)
NFKBIA [cytosol]
(R-HSA-168151)
p-S32,S36-NFKBIA [cytosol]
(R-HSA-177677)
Ub-21,22-p-S32,S36-NFKBIA [cytosol]
(R-HSA-1168581)
K48PolyUb-K21,22-p-S32,S36-IkBA [cytosol]
(R-HSA-5607659)
NFKBIA S32I [cytosol]
(R-HSA-5228846)
NFKBIA F2_M37del [cytosol]
(R-HSA-9630119)
NFKBIA M37K [cytosol]
(R-HSA-5228805)
NFKBIA [nucleoplasm]
(R-HSA-4656929)
0.556
3
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:Q16186 ADRM1
1
ADRM1 [cytosol]
(R-HSA-5665939)
0.527
3
UniProt:P16885 PLCG2
10
PLCG2 [plasma membrane]
(R-HSA-114601)
p-PLCG2 [plasma membrane]
(R-HSA-114602)
p-Y753,Y759,Y1217-PLCG2 [plasma membrane]
(R-HSA-984816)
PLCG2 [cytosol]
(R-HSA-984806)
PLCG2 [plasma membrane]
(R-HSA-2023875)
p-4Y-PLCG2 [plasma membrane]
(R-HSA-2685601)
p-Y753,Y759-PLCG2 [plasma membrane]
(R-HSA-5607640)
p-Y753,Y759-PLCG2 [cytosol]
(R-HSA-5607631)
PLCG2 [cytosol]
(R-HSA-1604645)
p-Y-PLCG2 [cytosol]
(R-HSA-9029105)
0.508
2
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