Reactome | PSMD13 [secretory granule lumen]

PSMD13 [secretory granule lumen]

Stable Identifier

R-HSA-6800983

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule lumen

Synonyms

26S proteasome non-ATPase regulatory subunit 13, 26S proteasome regulatory subunit S11, 26S proteasome regulatory subunit p40.5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UNM6 PSMD13

Gene Names

PSMD13

Chain

chain:1-376

Reference Genes

BioGPS Gene:5719 PSMD13

COSMIC (genes):PSMD13 PSMD13

CTD Gene:5719 PSMD13

dbSNP Gene:5719 PSMD13

ENSEMBL:ENSG00000185627.19 PSMD13

HGNC:9558 PSMD13

KEGG Gene (Homo sapiens):5719 PSMD13

Monarch:5719 PSMD13

NCBI Gene:5719 PSMD13

OMIM:603481 PSMD13

UCSC:Q9UNM6 PSMD13

Reference Transcript

Other Identifiers

0000130021

11719927_a_at

11741771_a_at

11756188_x_at

16720006

201232_PM_s_at

201232_s_at

201233_PM_at

201233_at

32211_at

3315550

3315551

3315552

3315554

3315555

3315556

3315557

3315558

3315559

3315562

3315564

3315567

3315572

3315574

3315576

3315577

5719

7937287

A_23_P75889

GE81196

GO:0000502

GO:0003674

GO:0005198

GO:0005575

GO:0005576

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005838

GO:0006511

GO:0007127

GO:0008150

GO:0008541

GO:0016020

GO:0022624

GO:0030163

GO:0031410

GO:0032991

GO:0034774

GO:0043161

GO:0043226

GO:1904813

HMNXSV003050587

ILMN_1704404

ILMN_2342121

PH_hs_0014359

TC11000006.hg

TC11002481.hg

g4506222_3p_s_at

Participates

as a member of

Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)

Other forms of this molecule

PSMD13 [extracellular region]

PSMD13 [ficolin-1-rich granule lumen]

PSMD13 [nucleoplasm]

PSMD13 [cytosol]

Inferred To

rpn-9 [secretory granule lumen] (Caenorhabditis elegans)

Rpn9 [secretory granule lumen] (Drosophila melanogaster)

psmd13 [secretory granule lumen] (Xenopus tropicalis)

RPN9 [secretory granule lumen] (Saccharomyces cerevisiae)

rpn9 [secretory granule lumen] (Schizosaccharomyces pombe)

psmD13 [secretory granule lumen] (Dictyostelium discoideum)

Psmd13 [secretory granule lumen] (Mus musculus)

Psmd13 [secretory granule lumen] (Rattus norvegicus)

PSMD13 [secretory granule lumen] (Bos taurus)

PSMD13 [secretory granule lumen] (Canis familiaris)

PSMD13 [secretory granule lumen] (Gallus gallus)

PSMD13 [secretory granule lumen] (Plasmodium falciparum)

PSMD13 [secretory granule lumen] (Sus scrofa)

zgc:56377 [secretory granule lumen] (Danio rerio)

Cross References

RefSeq

NP_787128.2, NP_002808.3

OpenTargets

ENSG00000185627

GeneCards

Q9UNM6

HPA

ENSG00000185627-PSMD13

Ensembl

ENSP00000396937, ENST00000532097, ENSG00000185627, ENSP00000436186, ENST00000431206

PRO

Q9UNM6

Pharos - Targets

Q9UNM6

PDB

6MSJ, 5GJR, 5T0H, 6MSH, 6MSG, 5T0I, 5T0J, 5VFQ, 5VFP, 5VHS, 5VHI, 6MSE, 6MSD, 5VHH, 5M32, 5T0G, 6WJD, 5GJQ, 5VFT, 6MSB, 5VHF, 5LN3, 5T0C, 5VFU, 6MSK, 5L4K, 6WJN, 5VFS, 5VFR, 5VGZ

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y4K3 TRAF6	8	K48polyUb-TRAF6 [cytosol] (R-HSA-6783233) PolyUb-TRAF6 [cytosol] (R-HSA-6782845) TRAF6 [endosome membrane] (R-HSA-450272) TRAF6 [cytosol] (R-HSA-166366) K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) TRAF6 [plasma membrane] (R-HSA-936955) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227)	0.589	2
UniProt:O00487 PSMD14	5	PSMD14 [secretory granule lumen] (R-HSA-6800926) PSMD14 [extracellular region] (R-HSA-6806511) PSMD14 [ficolin-1-rich granule lumen] (R-HSA-6800419) PSMD14 [nucleoplasm] (R-HSA-174329) PSMD14 [cytosol] (R-HSA-68722)	0.564	2
UniProt:P62333 PSMC6	2	PSMC6 [nucleoplasm] (R-HSA-174319) PSMC6 [cytosol] (R-HSA-68783)	0.553	2
UniProt:Q9Y5K5 UCHL5	2	UCHL5 [cytosol] (R-HSA-1629778) UCHL5 [nucleoplasm] (R-HSA-5689584)	0.527	3

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