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AMPD3 [secretory granule lumen]
Stable Identifier
R-HSA-6801064
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule lumen
Synonyms
AMP deaminase isoform E, AMP deaminase 3, erythrocyte AMP deaminase, AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (Erythrocyte AMP deaminase), Erythrocyte AMP deaminase
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
AMPD3 [secretory granule lumen] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
The Metabolic and Molecular Bases of Inherited Disease, 8th ed
Scriver, CR
,
Beaudet, AL
,
Valle, D
,
Sly, WS
2001
618880
Human erythrocyte 5'-AMP aminohydrolase. Purification and characterization.
Yun, S
,
Suelter, CH
J Biol Chem
1978
External Reference Information
External Reference
UniProt:Q01432 AMPD3
Gene Names
AMPD3
Chain
chain:1-767
Reference Genes
BioGPS Gene:272 AMPD3
COSMIC (genes):AMPD3 AMPD3
CTD Gene:272 AMPD3
dbSNP Gene:272 AMPD3
ENSEMBL:ENSG00000133805 AMPD3
HGNC:470 AMPD3
KEGG Gene (Homo sapiens):272 AMPD3
Monarch:272 AMPD3
NCBI Gene:272 AMPD3
OMIM:102772 AMPD3
UCSC:Q01432 AMPD3
Reference Transcript
RefSeq:NM_000480.2 AMPD3
RefSeq:NM_001025390.1 AMPD3
RefSeq:NM_001025389.1 AMPD3
RefSeq:NM_001172431.1 AMPD3
RefSeq:NM_001172430.1 AMPD3
Other Identifiers
0001230242
11734064_a_at
11734065_a_at
11739419_a_at
11739420_a_at
11741184_a_at
11749016_a_at
11758009_s_at
16721916
207992_s_at
209491_s_at
272
2817836
3320170
3320171
3320172
3320173
3320179
3320180
3320181
3320182
3320183
3320189
3320195
3320196
3320198
3320201
3320208
3320213
3320215
3320218
3320227
3320228
3320229
3320231
3320232
3320233
3320234
3320235
38463_s_at
4037701
7938396
A_14_P115542
A_14_P135756
A_23_P116286
A_24_P304154
D12775_s_at
GE60534
GO:0002376
GO:0003674
GO:0003876
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005829
GO:0006188
GO:0006196
GO:0006810
GO:0008150
GO:0009056
GO:0009058
GO:0009117
GO:0009168
GO:0016192
GO:0016787
GO:0016810
GO:0019239
GO:0031410
GO:0032264
GO:0034101
GO:0034641
GO:0034655
GO:0034774
GO:0042592
GO:0043101
GO:0043167
GO:0043226
GO:0043312
GO:0044281
GO:0046031
GO:0046033
GO:0046034
GO:0046039
GO:0046872
GO:0097009
GO:1904813
Hs.83918.1.S1_3p_a_at
ILMN_1660854
ILMN_1665307
ILMN_1731223
ILMN_1774447
PH_hs_0004781
TC11000184.hg
g4502078_3p_a_at
Participant Of
hasMember
Secretory granule lumen proteins [secretory granule lumen]
Other forms of this molecule
AMPD3 [ficolin-1-rich granule lumen]
AMPD3 [extracellular region]
AMPD3 [cytosol]
Inferred To
AMPdeam [secretory granule lumen] (Drosophila melanogaster)
ada1 [secretory granule lumen] (Schizosaccharomyces pombe)
ampd-1 [secretory granule lumen] (Caenorhabditis elegans)
AMPD3 [secretory granule lumen] (Bos taurus)
AMPD3 [secretory granule lumen] (Canis familiaris)
AMPD3 [secretory granule lumen] (Gallus gallus)
AMPD3 [secretory granule lumen] (Plasmodium falciparum)
AMPD3 [secretory granule lumen] (Saccharomyces cerevisiae)
AMPD3 [secretory granule lumen] (Sus scrofa)
AMPD3 [secretory granule lumen] (Xenopus tropicalis)
ampd3a [secretory granule lumen] (Danio rerio)
Homologues of AMPD3 [secretory granule lumen] (Saccharomyces cerevisiae)
AMD1 [secretory granule lumen] (Saccharomyces cerevisiae)
Ampd3 [secretory granule lumen] (Mus musculus)
Ampd3 [secretory granule lumen] (Rattus norvegicus)
amdA [secretory granule lumen] (Dictyostelium discoideum)
Cross References
RefSeq
NP_000471.1
,
NP_001020560.1
,
NP_001165901.1
,
NP_001165902.1
,
NP_001020561.1
OpenTargets
ENSG00000133805
ZINC - Substances
AMPD3_HUMAN
GeneCards
Q01432
HPA
ENSG00000133805-AMPD3
Ensembl
ENST00000529507
,
ENST00000444303
,
ENSP00000379801
,
ENSP00000379802
,
ENSP00000436987
,
ENSP00000396000
,
ENST00000528723
,
ENSP00000431648
,
ENST00000396553
,
ENST00000396554
,
ENSG00000133805
ZINC target
Q01432
PRO
Q01432
Orphanet
15928
ZINC - Predictions - Purchasable
AMPD3_HUMAN
HMDB Protein
HMDBP00597
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08238 HSP90AB1
6
HSP90AB1 [extracellular region]
(R-HSA-6806463)
HSP90AB1 [ficolin-1-rich granule lumen]
(R-HSA-6801491)
HSP90AB1 [secretory granule lumen]
(R-HSA-6801477)
HSP90AB1 [cytosol]
(R-HSA-419617)
HSP90AB1 [nucleoplasm]
(R-HSA-5082399)
HSP90AB1 [lysosomal lumen]
(R-HSA-9622846)
0.499
2
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