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HSPA6 [secretory granule lumen]
Stable Identifier
R-HSA-6801472
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule lumen
Synonyms
Heat shock 70 kDa protein 6
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
HSPA6 [secretory granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P17066 HSPA6
Gene Names
HSPA6, HSP70B'
Chain
chain:1-643
Reference Genes
BioGPS Gene:3310 HSPA6
COSMIC (genes):HSPA6 HSPA6
CTD Gene:3310 HSPA6
dbSNP Gene:3310 HSPA6
ENSEMBL:ENSG00000173110 HSPA6
HGNC:5239 HSPA6
KEGG Gene (Homo sapiens):3310 HSPA6
Monarch:3310 HSPA6
NCBI Gene:3310 HSPA6
OMIM:140555 HSPA6
UCSC:P17066 HSPA6
Reference Transcript
RefSeq:NM_002155.4 HSPA6
Other Identifiers
0003140403
11723050_a_at
11757367_s_at
117_3p_at
117_at
16672914
213418_at
2363785
2363786
2363787
2363788
2363789
2363790
2363791
2363792
2363793
2363794
2363795
2363796
2363797
3310
35965_at
56711_s_at
7906764
7906775
A_14_P107820
A_23_P114903
GE59761
GO:0000166
GO:0002376
GO:0003674
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005814
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0006457
GO:0006810
GO:0006950
GO:0006986
GO:0008150
GO:0008180
GO:0016192
GO:0016887
GO:0019899
GO:0031072
GO:0031410
GO:0031625
GO:0032991
GO:0034605
GO:0034620
GO:0034774
GO:0042026
GO:0043167
GO:0043226
GO:0043312
GO:0044183
GO:0051082
GO:0051085
GO:0051787
GO:0070062
GO:0072562
GO:1904813
Hs.3268.0.S1_3p_at
ILMN_1658383
ILMN_1806165
ILMN_3247458
PH_hs_0000400
TC01001401.hg
TC01004796.hg
X51757_at
X51757cds_3p_at
X51757cds_3p_s_at
Participant Of
hasMember
Secretory granule lumen proteins [secretory granule lumen]
Other forms of this molecule
HSPA6 [cytosol]
HSPA6 [nucleoplasm]
HSPA6 [ficolin-1-rich granule lumen]
HSPA6 [extracellular region]
Inferred To
Hsp70Ba [secretory granule lumen] (Drosophila melanogaster)
Hsp70Bc [secretory granule lumen] (Drosophila melanogaster)
SSA3 [secretory granule lumen] (Saccharomyces cerevisiae)
ssa2 [secretory granule lumen] (Schizosaccharomyces pombe)
Hsp70Ab [secretory granule lumen] (Drosophila melanogaster)
hspB [secretory granule lumen] (Dictyostelium discoideum)
hsp70.3 [secretory granule lumen] (Danio rerio)
Hsc70-2 [secretory granule lumen] (Drosophila melanogaster)
ssa1 [secretory granule lumen] (Schizosaccharomyces pombe)
Hsp68 [secretory granule lumen] (Drosophila melanogaster)
hspE-2 [secretory granule lumen] (Dictyostelium discoideum)
hsp70l [secretory granule lumen] (Danio rerio)
SSA2 [secretory granule lumen] (Saccharomyces cerevisiae)
hspa1b [secretory granule lumen] (Danio rerio)
hspa1b [secretory granule lumen] (Xenopus tropicalis)
Hsp70Bb [secretory granule lumen] (Drosophila melanogaster)
Hsp70Bbb [secretory granule lumen] (Drosophila melanogaster)
HSPA6 [secretory granule lumen] (Bos taurus)
HSPA6 [secretory granule lumen] (Dictyostelium discoideum)
HSPA6 [secretory granule lumen] (Plasmodium falciparum)
HSPA6 [secretory granule lumen] (Xenopus tropicalis)
SSA4 [secretory granule lumen] (Saccharomyces cerevisiae)
hsp70 [secretory granule lumen] (Xenopus tropicalis)
Homologues of HSPA6 [secretory granule lumen] (Danio rerio)
Homologues of HSPA6 [secretory granule lumen] (Dictyostelium discoideum)
Homologues of HSPA6 [secretory granule lumen] (Drosophila melanogaster)
Homologues of HSPA6 [secretory granule lumen] (Saccharomyces cerevisiae)
Homologues of HSPA6 [secretory granule lumen] (Schizosaccharomyces pombe)
Homologues of HSPA6 [secretory granule lumen] (Xenopus tropicalis)
hsp70.2 [secretory granule lumen] (Danio rerio)
Hsp70Aa [secretory granule lumen] (Drosophila melanogaster)
SSA1 [secretory granule lumen] (Saccharomyces cerevisiae)
Cross References
RefSeq
NP_002146.2
OpenTargets
ENSG00000173110
HPA
ENSG00000173110-HSPA6
GeneCards
P17066
Ensembl
ENSP00000310219
,
ENSG00000173110
,
ENST00000309758
PRO
P17066
PDB
3FE1
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99558 MAP3K14
5
MAP3K14 [cytosol]
(R-HSA-168189)
Active NIK [cytosol]
(R-HSA-5607646)
p-MAP3K14 [cytosol]
(R-HSA-168187)
K48polyUb-NIK [cytosol]
(R-HSA-5668525)
p-T559-MAP3K14 [cytosol]
(R-HSA-5668531)
0.564
3
UniProt:P27694 RPA1
2
RPA1 [nucleoplasm]
(R-HSA-68461)
SUMO2,3-K449,K577-RPA1 [nucleoplasm]
(R-HSA-4551644)
0.556
3
UniProt:O95429 BAG4
3
BAG4(1-126):p-8Y FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853156)
BAG4 [cytosol]
(R-HSA-5212670)
BAG4(1-126):FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853157)
0.556
3
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