Reactome | DYNLT1 [secretory granule lumen]

DYNLT1 [secretory granule lumen]

Stable Identifier

R-HSA-6801497

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule lumen

Synonyms

Dynein light chain Tctex-type 1, DYLT1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P63172 DYNLT1

Gene Names

DYNLT1, TCTEL1, TCTEX-1, TCTEX1

Chain

chain:1-113

Reference Genes

BioGPS Gene:6993 DYNLT1

COSMIC (genes):DYNLT1 DYNLT1

CTD Gene:6993 DYNLT1

dbSNP Gene:6993 DYNLT1

ENSEMBL:ENSG00000146425 DYNLT1

HGNC:11697 DYNLT1

KEGG:hsa:6993 DYNLT1

Monarch:6993 DYNLT1

NCBI Gene:6993 DYNLT1

OMIM:601554 DYNLT1

UCSC:P63172 DYNLT1

Reference Transcript

RefSeq:NM_006519.3 DYNLT1

Other Identifiers

11716583_a_at

11716584_x_at

11753785_x_at

17025177

201999_PM_s_at

201999_s_at

2981875

2981876

2981877

2981878

2981879

2981880

2981881

2981882

2981885

2981886

2981889

2981890

3710718

6993

8130499

946_at

A_23_P8185

A_33_P3260445

D50663_at

GE61149

GO:0000132

GO:0005515

GO:0005576

GO:0005737

GO:0005794

GO:0005819

GO:0005856

GO:0005868

GO:0005874

GO:0005881

GO:0007010

GO:0007018

GO:0007399

GO:0008277

GO:0019060

GO:0030286

GO:0031410

GO:0034774

GO:0042802

GO:0043226

GO:0043657

GO:0045505

GO:0046718

GO:0048856

GO:0050768

GO:0051301

GO:0075521

GO:0099503

GO:1904813

HMNXSV003011447

HMNXSV003016472

ILMN_1678766

PH_hs_0013701

TC06002263.hg

g5730084_3p_a_at

Participates

as a member of

Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)

Other forms of this molecule

DYNLT1 [ficolin-1-rich granule lumen]

DYNLT1 [extracellular region]

Inferred To

Homologues of DYNLT1 [secretory granule lumen] (Bos taurus)

dylt-1 [secretory granule lumen] (Caenorhabditis elegans)

dynlt1 [secretory granule lumen] (Xenopus tropicalis)

DYNLT1 [secretory granule lumen] (Bos taurus)

DYNLT1 [secretory granule lumen] (Canis familiaris)

DYNLT1 [secretory granule lumen] (Gallus gallus)

DYNLT1 [secretory granule lumen] (Plasmodium falciparum)

DYNLT1 [secretory granule lumen] (Sus scrofa)

Dlc90F [secretory granule lumen] (Drosophila melanogaster)

dlc1 [secretory granule lumen] (Schizosaccharomyces pombe)

Dynlt1 [secretory granule lumen] (Mus musculus)

Dynlt1 [secretory granule lumen] (Rattus norvegicus)

dlcA [secretory granule lumen] (Dictyostelium discoideum)

Cross References

ENSEMBL

ENSP00000356056, ENST00000367089

OpenTargets

ENSG00000146425

HPA

ENSG00000146425-DYNLT1

PRO

P63172

Pharos - Targets

P63172

GlyGen

P63172

PDB

8PR1, 8RGI, 8PTK, 5JPW, 8PR0, 8J07

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:P12814 ACTN1	3	ACTN1 [cytosol] (R-HSA-354096) ACTN1 [platelet alpha granule lumen] (R-HSA-349724) ACTN1 [extracellular region] (R-HSA-349722)	0.556	3
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.556	3
UniProt:P08670 VIM	11	Vimentin [lysosomal lumen] (R-HSA-9659977) Vimentin [cytosol] (R-HSA-9646687) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [late endosome lumen] (R-HSA-9660019) VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-429) [cytosol] (R-HSA-350317) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294) VIM(2-85) [cytosol] (R-HSA-350264)	0.508	2
UniProt:P43034 PAFAH1B1	1	PAFAH1B1 [cytosol] (R-HSA-376249)	0.508	2
UniProt:Q99873 PRMT1	2	PRMT1 [nucleoplasm] (R-HSA-3215140) PRMT1 [cytosol] (R-HSA-9632173)	0.508	2

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