Reactome | DBNL [ficolin-1-rich granule lumen]

DBNL [ficolin-1-rich granule lumen]

Stable Identifier

R-HSA-6801510

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ficolin-1-rich granule lumen

Synonyms

HIP-55

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UJU6 DBNL

Gene Names

DBNL, CMAP, SH3P7, PP5423

Chain

chain:1-430

Reference Genes

COSMIC (genes):DBNL DBNL

ENSEMBL:ENSG00000136279 DBNL

HGNC:2696 DBNL

UCSC:Q9UJU6 DBNL

Other Identifiers

11740992_x_at

11747076_a_at

11748558_a_at

11748559_x_at

11750282_x_at

11756792_x_at

11757879_s_at

17045599

222429_PM_at

222429_at

28988

2999711

2999712

2999713

2999714

2999715

2999716

2999717

2999718

2999719

2999721

2999722

2999723

2999724

2999725

2999726

2999727

2999728

2999729

2999730

2999731

2999732

2999733

2999734

2999736

2999738

2999740

2999742

2999743

2999744

2999745

2999746

2999747

2999748

2999749

2999750

2999751

2999752

2999754

48577_at

67173_at

8132539

88842_r_at

A_14_P134457

A_14_P134641

A_23_P168692

A_24_P43681

A_33_P3211260

A_33_P3295009

GE479780

GE81857

GE86253

GE86342

GO:0000139

GO:0001726

GO:0002102

GO:0002250

GO:0002376

GO:0003779

GO:0005198

GO:0005515

GO:0005576

GO:0005737

GO:0005768

GO:0005769

GO:0005794

GO:0005829

GO:0005856

GO:0005886

GO:0005938

GO:0006897

GO:0007010

GO:0007416

GO:0008047

GO:0008092

GO:0014069

GO:0016020

GO:0016192

GO:0016601

GO:0019904

GO:0030027

GO:0030425

GO:0030665

GO:0031410

GO:0034330

GO:0034774

GO:0042995

GO:0043204

GO:0043226

GO:0043231

GO:0045202

GO:0045296

GO:0048812

GO:0051015

GO:0061024

GO:0065003

GO:0070062

GO:0070161

GO:0071800

GO:0098772

GO:0098793

GO:0098794

GO:0098973

GO:0098974

GO:0098978

GO:1904724

GO:1904813

HMNXSV003020595

HMNXSV003022481

HMNXSV003037724

HMNXSV003053749

ILMN_1698307

ILMN_2376289

PH_hs_0010817

TC07003393.hg

g8885629_3p_at

p29474

Participates

as a member of

Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)

Other forms of this molecule

DBNL [tertiary granule lumen]

DBNL [extracellular region]

DBNL [secretory granule lumen]

DBNL(1-361) [cytosol]

DBNL(362-431) [cytosol]

DBNL [cytosol]

Inferred To

SORBS2 [ficolin-1-rich granule lumen] (Bos taurus)

SORBS2 [ficolin-1-rich granule lumen] (Canis familiaris)

SORBS2 [ficolin-1-rich granule lumen] (Sus scrofa)

PIN3 [ficolin-1-rich granule lumen] (Saccharomyces cerevisiae)

Sorbs2 [ficolin-1-rich granule lumen] (Mus musculus)

Sorbs2 [ficolin-1-rich granule lumen] (Rattus norvegicus)

sorb-1 [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

Homologues of DBNL [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

Homologues of DBNL [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

DBNL [ficolin-1-rich granule lumen] (Caenorhabditis elegans)

DBNL [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

DBNL [ficolin-1-rich granule lumen] (Gallus gallus)

CAP [ficolin-1-rich granule lumen] (Drosophila melanogaster)

sfp47 [ficolin-1-rich granule lumen] (Schizosaccharomyces pombe)

Cross References

ENSEMBL

ENSP00000411701, ENST00000490734, ENSP00000419992, ENST00000456905, ENSP00000416421, ENST00000468694, ENSP00000417653, ENST00000448521, ENST00000494774, ENSP00000417749, ENSP00000415173, ENST00000440166

OpenTargets

ENSG00000136279

HPA

ENSG00000136279-DBNL

PRO

Q9UJU6

Pharos - Targets

Q9UJU6

GlyGen

Q9UJU6

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H788 SH24A			0.764	6
UniProt:P78314 3BP2			0.659	7
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	11
UniProt:Q96JN8 NEUL4			0.564	3
UniProt:O95714 HERC2	5	HERC2 [nucleoplasm] (R-HSA-4551680) p-T4827-HERC2 [nucleoplasm] (R-HSA-5682601) p-T4827,SUMO1-HERC2 [nucleoplasm] (R-HSA-5682615) HERC2 [cytosol] (R-HSA-975975) monoSUMO1-HERC2 [nucleoplasm] (R-HSA-4551758)	0.564	3
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959)	0.556	3
UniProt:P06396 GSN	7	GSN [cytosol] (R-HSA-350275) GSN(28-403) [cytosol] (R-HSA-201618) GSN(404-782) [cytosol] (R-HSA-350272) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(200-270) [extracellular region] (R-HSA-976940)	0.556	3
UniProt:Q9H788-2 SH2D4A			0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189)	0.556	3
UniProt:P46379-2 BAG6			0.556	3
UniProt:O14645 IDLC			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q96AP0 ACD	1	ACD [nucleoplasm] (R-HSA-174889)	0.508	2
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.483	2

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