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CTSH(116-335) [extracellular region]
Stable Identifier
R-HSA-6801616
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Cathepsin H, Cathepsin H component recommendedName: Cathepsin H mini chain /component component recommendedName: Cathepsin H heavy chain /component component recommendedName: Cathepsin H light chain /component, CTSH, CATH_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule lumen proteins (Homo sapiens)
Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)
CTSH(116-335) [extracellular region] (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [extracellular region] (Homo sapiens)
CTSH(116-335) [extracellular region] (Homo sapiens)
Exocytosis of tertiary granule lumen proteins (Homo sapiens)
Tertiary granule lumen proteins [extracellular region] (Homo sapiens)
CTSH(116-335) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09668 CTSH
Gene Names
CTSH, CPSB
Chain
signal peptide:1-22, propeptide:23-97, peptide:98-105, propeptide:106-115, chain:116-335, chain:116-292, chain:293-335
Reference Genes
BioGPS Gene:1512 CTSH
COSMIC (genes):CTSH CTSH
CTD Gene:1512 CTSH
dbSNP Gene:1512 CTSH
ENSEMBL:ENSG00000103811 CTSH
ENSEMBL_homo_sapiens_GENE:ENSG00000103811.18 CTSH
HGNC:2535 CTSH
KEGG Gene (Homo sapiens):1512 CTSH
Monarch:1512 CTSH
NCBI Gene:1512 CTSH
OMIM:116820 CTSH
UCSC:P09668 CTSH
Reference Transcript
RefSeq:NM_004390.4 CTSH
Other Identifiers
11757383_a_at
1512
202295_PM_s_at
202295_s_at
3634816
3634817
3634818
3634820
3634823
3634825
3634827
3634829
3634831
3634835
3634836
3634838
3634841
3634845
3634846
3634847
3634848
37021_at
7990757
A_23_P14774
GE59742
GE86875
GO:0001656
GO:0001913
GO:0002250
GO:0002376
GO:0002764
GO:0003824
GO:0004175
GO:0004177
GO:0004197
GO:0004252
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005768
GO:0005773
GO:0005829
GO:0006508
GO:0006915
GO:0006955
GO:0008233
GO:0008234
GO:0008284
GO:0008656
GO:0010628
GO:0010634
GO:0010813
GO:0010815
GO:0010952
GO:0012501
GO:0016505
GO:0016787
GO:0019882
GO:0023052
GO:0030108
GO:0030163
GO:0030312
GO:0030335
GO:0031012
GO:0031410
GO:0031638
GO:0031648
GO:0032526
GO:0033619
GO:0034774
GO:0036464
GO:0043066
GO:0043129
GO:0043226
GO:0043231
GO:0045766
GO:0048856
GO:0048870
GO:0051603
GO:0051604
GO:0060089
GO:0060448
GO:0062023
GO:0070062
GO:0070324
GO:0070371
GO:0097067
GO:0097208
GO:0097486
GO:0098772
GO:0140096
GO:1904724
GO:1904813
GO:2001235
HMNXSV003010880
ILMN_1752451
ILMN_2390853
PH_hs_0022310
TC15001713.hg
TC15002646.hg
X16832_at
g4758095_3p_s_at
Participates
as a member of
Secretory granule lumen proteins [extracellular region] (Homo sapiens)
Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)
Tertiary granule lumen proteins [extracellular region] (Homo sapiens)
Other forms of this molecule
CTSH(116-335) [lysosomal lumen]
CTSH(293-335) [multivesicular body lumen]
CTSH(116-292) [multivesicular body lumen]
CTSH(98-105) [multivesicular body lumen]
CTSH(116-335) [secretory granule lumen]
CTSH(116-335) [ficolin-1-rich granule lumen]
CTSH(116-335) [tertiary granule lumen]
Inferred To
CTSH(116-335) [extracellular region]
(Gallus gallus)
CTSH [extracellular region]
(Bos taurus)
CTSH [extracellular region]
(Canis familiaris)
CTSH [extracellular region]
(Sus scrofa)
ctsh [extracellular region]
(Danio rerio)
Ctsh [extracellular region]
(Mus musculus)
Ctsh [extracellular region]
(Rattus norvegicus)
Cross References
RefSeq
NP_004381.2
Guide to Pharmacology - Targets
2349
OpenTargets
ENSG00000103811
ZINC - Substances
CATH_HUMAN
ZINC target
P09668
PRO
P09668
PDB
6CZK
,
6CZS
GeneCards
P09668
HPA
ENSG00000103811-CTSH
Ensembl
ENSP00000220166
,
ENSG00000103811
,
ENST00000220166
Pharos - Targets
P09668
ZINC - Predictions - Purchasable
CATH_HUMAN
Orphanet
22533
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15915 ZIC1
1
ZIC1 [nucleoplasm]
(R-HSA-9731648)
0.527
2
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