PLK2 phosphorylates CENPJ

Stable Identifier
R-HSA-6801666
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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PLK2 phosphorylates centrosome protein CENPJ (CPAP) on serine residues S589 and S585, which is a prerequisite for procentriole formation and centrosome duplication (Chang et al. 2010).

Literature References
PubMed ID Title Journal Year
20531387 PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle

Chang, J, Cizmecioglu, O, Hoffmann, I, Rhee, K

EMBO J. 2010
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of PLK2 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created