PLK2 phosphorylates NPM1

Stable Identifier
R-HSA-6801675
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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PLK2 phosphorylates NPM1 (nucleophosmin) on serine residue S4, which may be necessary to trigger centrosome duplication (Krause and Hoffmann 2010).

Literature References
PubMed ID Title Journal Year
20352051 Polo-like kinase 2-dependent phosphorylation of NPM/B23 on serine 4 triggers centriole duplication

Krause, A, Hoffmann, I

PLoS ONE 2010
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of PLK2 [cytosol]

Orthologous Events
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