ESRP1-RAF1 fusion [cytosol]

Stable Identifier
R-HSA-6802312
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
20526349 Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

Palanisamy, N, Ateeq, B, Kalyana-Sundaram, S, Pflueger, D, Ramnarayanan, K, Shankar, S, Han, B, Cao, Q, Cao, X, Suleman, K, Kumar-Sinha, C, Dhanasekaran, SM, Chen, YB, Esgueva, R, Banerjee, S, Lafargue, CJ, Siddiqui, J, Demichelis, F, Moeller, P, Bismar, TA, Kuefer, R, Fullen, DR, Johnson, TM, Greenson, JK, Giordano, TJ, Tan, P, Tomlins, SA, Varambally, S, Rubin, MA, Maher, CA, Chinnaiyan, AM

Nat. Med. 2010
External Reference Information
External Reference
Gene Names
ESRP1, RBM35A
Chain
chain:1-681
Other Identifiers
0000070402
11723543_a_at
11723544_a_at
17070949
219121_s_at
225846_at
3107549
3107550
3107552
3107554
3107555
3107563
3107564
3107565
3107566
3107567
3107568
3107570
3107571
3107578
3107585
3107586
3107587
3107590
3107593
3107594
3631959
50391_at
54845
8147351
82072_at
A_14_P135791
A_23_P259127
GE55386
GO:0003674
GO:0003676
GO:0003723
GO:0003729
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0006397
GO:0007165
GO:0008150
GO:0008380
GO:0008543
GO:0016604
GO:0030154
GO:0034641
GO:0042669
GO:0043226
GO:0043484
GO:0048856
Hs.24743.1.A1_3p_at
ILMN_1749180
PH_hs_0002178
TC08000575.hg
g8923166_3p_a_at
Participant Of
Other forms of this molecule
Modified Residues
Name
Insertion of residues 227 to 648 at 607 from UniProt:P04049 RAF1
Coordinate
607
Name
O-phospho-L-serine at 621
Coordinate
621
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
prostate cancer 10283 NGP - New growth of prostate, neoplasm of prostate (disorder), tumor of the prostate, malignant tumor of prostate (disorder), prostate neoplasm, malignant tumor of the prostate, malignant tumor of prostate (disorder), prostatic cancer, prostatic neoplasm
cancer 162 malignant tumor, malignant neoplasm, primary cancer
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