FAM114A2(1-327)-BRAF(439-766) fusion [cytosol]

Stable Identifier
R-HSA-6802321
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Kim, JL, Schalm, S, Stransky, N, Lengauer, C, Cerami, E

Nat Commun 2014
External Reference Information
External Reference
UniProt:Q9NRY5 FAM114A2
Gene Names
FAM114A2, C5orf3
Chain
chain:1-505
Reference Genes
BioGPS Gene:10827 FAM114A2
COSMIC (genes):FAM114A2 FAM114A2
CTD Gene:10827 FAM114A2
dbSNP Gene:10827 FAM114A2
ENSEMBL:ENSG00000055147 FAM114A2
ENSEMBL_homo_sapiens_GENE:ENSG00000055147.19 FAM114A2
HGNC:1333 FAM114A2
KEGG Gene (Homo sapiens):10827 FAM114A2
Monarch:10827 FAM114A2
NCBI Gene:10827 FAM114A2
UCSC:Q9NRY5 FAM114A2
Reference Transcript
Other Identifiers
10827
11730797_a_at
11730798_a_at
11751327_a_at
17002004
218588_PM_s_at
218588_s_at
222682_PM_s_at
222682_s_at
2882577
2882578
2882579
2882580
2882581
2882582
2882583
2882584
2882585
2882586
2882587
2882589
2882591
2882593
2882594
2882595
2882598
2882600
2882602
2882604
2882605
2882606
2882607
2882608
2882609
2882610
2882611
2882614
2882615
2882616
2882617
65462_at
78545_at
8115375
81275_at
82184_at
A_23_P41908
GE82439
GO:0005515
GO:0005575
GO:0008150
GO:0017076
HMNXSV003038806
Hs.166551.0.S1_3p_a_at
ILMN_1675701
PH_hs_0010024
TC05001966.hg
g8922068_3p_a_at
Participates
as a component of
Other forms of this molecule
FAM114A2(1-327)-p-BRAF(439-766) fusion [cytosol]
Modified Residues
Name
Insertion of residues 439 to 766 at 328 from UniProt:P15056 BRAF
Coordinate
328
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
thyroid carcinoma DOID:3963 head and neck cancer, Thyroid
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Interactors (4)
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