HRAS G12V [plasma membrane]

Stable Identifier
R-HSA-6802350
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
HRAS, HRAS1
Chain
chain:1-186, initiator methionine:, chain:2-186, propeptide:187-189
Other Identifiers
11733320_a_at
11744709_a_at
1590_s_at
16733952
212983_PM_at
212983_at
3265
3358091
3358092
3358093
3358094
3358096
3358097
3358098
3358099
3358100
3358103
35701_at
7945436
A_23_P98183
GE57461
GO:0000139
GO:0000165
GO:0000166
GO:0001934
GO:0002376
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006357
GO:0006886
GO:0006897
GO:0006935
GO:0007010
GO:0007165
GO:0007166
GO:0007264
GO:0007265
GO:0008284
GO:0008285
GO:0008286
GO:0009887
GO:0010628
GO:0010629
GO:0010863
GO:0012501
GO:0016020
GO:0016192
GO:0016787
GO:0019003
GO:0023052
GO:0030335
GO:0032729
GO:0032956
GO:0034260
GO:0036211
GO:0042060
GO:0042088
GO:0042127
GO:0042832
GO:0043226
GO:0043405
GO:0043406
GO:0043410
GO:0043495
GO:0043524
GO:0043547
GO:0045944
GO:0046330
GO:0048144
GO:0048146
GO:0048169
GO:0048471
GO:0048856
GO:0048870
GO:0050679
GO:0050852
GO:0051402
GO:0051726
GO:0060090
GO:0060612
GO:0070374
GO:0071480
GO:0090303
GO:0090314
GO:0090398
GO:0090402
GO:0097193
GO:0098542
GO:0098696
GO:0098772
GO:0098978
GO:1900029
GO:1905360
GO:2000630
HMNXSV003016066
Hs.37003.0.S1_3p_at
Hs.37003.0.S1_3p_x_at
ILMN_1699798
ILMN_1773751
J00277_at
PH_hs_0031161
TC11001236.hg
V00574_s_at
Participates
Other forms of this molecule
Modified Residues
Name
glycine 12 replaced with L-valine
Coordinate
12
PsiMod
A protein modification that effectively converts a source amino acid residue to an L-valine.
A protein modification that effectively removes or replaces an glycine.
Disease
Name Identifier Synonyms
bladder carcinoma DOID:4007 carcinoma of urinary bladder, carcinoma bladder, carcinoma OF BLADDER, carcinoma of bladder (disorder), carcinoma bladder
melanoma DOID:1909 Naevocarcinoma, melanoma, melanoma, malignant melanoma, morphology (morphologic abnormality), malignant melanoma NOS (morphologic abnormality), malignant melanoma (disorder), malignant melanoma, malignant melanoma, malignant melanoma, malignant melanoma
thyroid cancer DOID:1781 Thyroid gland neoplasm, thyroid cancer, thyroid neoplasm, neoplasm of thyroid gland, thyroid neoplasm, Thyroid neoplasm, malignant tumour of thyroid gland, malignant neoplasm of thyroid gland
larynx cancer DOID:2596
Cross References
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
ZINC - Investigational
COSMIC
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (31)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04049 RAF1  20 0.978 30
 UniProt:Q07889 SOS1  3 0.938 11
 UniProt:P15056 BRAF  20 0.871 7
 UniProt:Q12967 RALGDS  1 0.683 3
 UniProt:Q9NZL6 RGL1  1 0.667 3
 UniProt:Q8WUX9 CHMP7  2 0.659 4
 UniProt:P21359 NF1  20 0.604 3
 UniProt:P42337 Pik3ca  1 0.589 3
 UniProt:Q9Y5Z9 UBIAD1  1 0.581 9
 UniProt:P11233 RALA  2 0.571 2
 UniProt:P12931 SRC  6 0.571 2
 UniProt:O95674 CDS2  1 0.556 3
 UniProt:Q13352 ITGB3BP  2 0.556 3
 UniProt:Q00994 BEX3  1 0.556 3
 UniProt:P22415 USF1  1 0.556 3
 UniProt:Q9BXU0 TEX12  1 0.556 3
 UniProt:O14641 DVL2  5 0.556 3
 UniProt:P24941 CDK2  5 0.556 3
 UniProt:Q13573 SNW1  1 0.556 3
 UniProt:A0AVK6 E2F8  1 0.556 3
 UniProt:Q99558 MAP3K14  5 0.556 3
 UniProt:O15534 PER1  4 0.556 3
 UniProt:Q9EQZ6  1 0.556 3
 UniProt:Q8N5V2 NGEF  2 0.556 3
 UniProt:Q96EZ8 MCRS1  1 0.556 3
 UniProt:O75528 TADA3  1 0.556 3
 UniProt:P10809 HSPD1  6 0.556 3
 UniProt:Q7Z569 BRAP  2 0.524 3
 UniProt:Q03135 CAV1  5 0.508 2
 UniProt:Q16850 CYP51A1  1 0.483 2
 UniProt:P42684 ABL2  1 0.462 2
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