p-AGTRAP-BRAF fusion [cytosol]

Stable Identifier
R-HSA-6802511
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
20526349 Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

Palanisamy, N, Ateeq, B, Kalyana-Sundaram, S, Pflueger, D, Ramnarayanan, K, Shankar, S, Han, B, Cao, Q, Cao, X, Suleman, K, Kumar-Sinha, C, Dhanasekaran, SM, Chen, YB, Esgueva, R, Banerjee, S, Lafargue, CJ, Siddiqui, J, Demichelis, F, Moeller, P, Bismar, TA, Kuefer, R, Fullen, DR, Johnson, TM, Greenson, JK, Giordano, TJ, Tan, P, Tomlins, SA, Varambally, S, Rubin, MA, Maher, CA, Chinnaiyan, AM

Nat. Med. 2010
External Reference Information
External Reference
Gene Names
AGTRAP, ATRAP
Chain
chain:1-159
Other Identifiers
0001170053
11727478_a_at
11753685_a_at
11753686_s_at
11753687_x_at
1555736_a_at
16659054
225059_at
2320412
2320413
2320417
2320420
2320421
2320423
2320424
2320425
56548_at
57085
7897745
GE62121
GE82526
GO:0000139
GO:0001666
GO:0003013
GO:0003674
GO:0004945
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005886
GO:0005938
GO:0006950
GO:0007165
GO:0008150
GO:0008217
GO:0016020
GO:0016021
GO:0030659
GO:0031410
GO:0038166
GO:0043226
GO:0043231
Hs.12854.0.S2_3p_at
Hs2.12854.2.S1_3p_s_at
ILMN_1802458
ILMN_2307656
PH_hs_0001230
TC01000147.hg
Participant Of
Other forms of this molecule
Modified Residues
Name
Insertion of residues 288 to 545 at 160 from UniProt:P15056 BRAF
Coordinate
160
Name
O-phospho-L-serine at 445
Coordinate
445
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 599
Coordinate
599
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 602
Coordinate
602
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
gastric adenocarcinoma 3717 adenocarcinoma of stomach (disorder), stomach adenocarcinoma
Interactors (15)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96PE7 MCEE  1 0.666 4
 UniProt:P53365 ARFIP2  1 0.666 4
 UniProt:Q8IWL3 HSCB  5 0.666 4
 UniProt:Q96CM8 ACSF2  1 0.666 4
 UniProt:Q9UKL6 PCTP  1 0.556 3
 UniProt:O95363 FARS2  1 0.556 3
 UniProt:O95971 CD160  1 0.556 3
 UniProt:Q00059 TFAM  2 0.556 3
 UniProt:Q99757 TXN2  3 0.556 3
 UniProt:P49590 HARS2  1 0.556 3
 UniProt:Q96E29 MTERF3  2 0.556 3
 UniProt:Q99259 GAD1  2 0.556 3
 UniProt:P09429 HMGB1  5 0.556 3
 UniProt:Q6IN84 MRM1  1 0.556 3
 UniProt:Q05329 GAD2  2 0.556 3
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