p-BCL2L11-BRAF fusion [cytosol]

Stable Identifier
R-HSA-6802519
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Stransky, N, Cerami, E, Schalm, S, Kim, JL, Lengauer, C

Nat Commun 2014
External Reference Information
External Reference
Gene Names
BCL2L11, BIM
Chain
chain:1-198
Other Identifiers
0002350369
10018
11718078_a_at
11718079_a_at
11718080_a_at
11735894_a_at
11735895_at
11745162_s_at
11751830_a_at
11753710_x_at
11753863_s_at
11759889_a_at
11763068_at
11763069_x_at
11763147_x_at
1553088_a_at
1553096_s_at
1558143_a_at
208536_s_at
222343_at
225606_at
2500276
2500278
2500279
2500280
2500281
2500290
2500291
2500297
2500300
2500301
2500303
2500305
2500306
2500307
2500308
2500309
31611_s_at
33047_at
57243_at
60188_at
60189_g_at
65960_at
8044375
A_23_P154426
A_23_P309991
A_23_P309996
A_23_P425954
A_24_P122921
A_33_P3251932
A_33_P3398526
GE87423
GE890567
GO:0000003
GO:0001701
GO:0001776
GO:0001782
GO:0001783
GO:0001822
GO:0001844
GO:0002260
GO:0002262
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005739
GO:0005741
GO:0005829
GO:0006810
GO:0006914
GO:0006915
GO:0006950
GO:0007005
GO:0007049
GO:0007127
GO:0007155
GO:0007160
GO:0007165
GO:0007283
GO:0007420
GO:0008017
GO:0008092
GO:0008150
GO:0008219
GO:0008584
GO:0008630
GO:0009056
GO:0009790
GO:0009791
GO:0010942
GO:0012505
GO:0016020
GO:0019898
GO:0019899
GO:0019901
GO:0022607
GO:0030879
GO:0031334
GO:0032991
GO:0034263
GO:0034976
GO:0035148
GO:0040007
GO:0042475
GO:0042592
GO:0042981
GO:0043029
GO:0043065
GO:0043226
GO:0043231
GO:0043280
GO:0043473
GO:0043525
GO:0043583
GO:0044403
GO:0045787
GO:0046620
GO:0048066
GO:0048070
GO:0048536
GO:0048538
GO:0048563
GO:0048646
GO:0048856
GO:0060139
GO:0061024
GO:0065003
GO:0070242
GO:0071385
GO:0071392
GO:0090200
GO:0097136
GO:0097192
GO:1902110
GO:1902237
GO:1902263
GO:1903896
GO:1904646
GO:2000271
GO:2001244
Hs.50760.0.A1_3p_at
Hs.84063.0.S1_3p_at
Hs2.202657.5.S1_3p_s_at
Hs2.202657.7.S1_3p_s_at
Hs2.84063.1.A1_3p_s_at
ILMN_1766541
ILMN_1774997
ILMN_2359627
PH_hs_0022197
g5729739_3p_s_at
Participant Of
Other forms of this molecule
Modified Residues
Name
Insertion of residues 397 to 766 at 132 from UniProt:P15056 BRAF
Coordinate
132
Name
O-phospho-L-serine at 445
Coordinate
445
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 599
Coordinate
599
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 602
Coordinate
602
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
thyroid carcinoma 3963 head and neck cancer, Thyroid
Interactors (21)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q07812 BAX  3 0.945 22
 UniProt:Q07820 MCL1  1 0.943 16
 UniProt:Q07817-1 BCL2L1      0.935 10
 UniProt:P10415 BCL2  1 0.918 8
 UniProt:Q92843 B2CL2      0.866 9
 UniProt:P97287 MCL1      0.796 7
 UniProt:Q9HD36 B2L10      0.78 10
 UniProt:Q07817 BCL2L1  1 0.775 8
 UniProt:Q16548 B2LA1      0.683 4
 UniProt:P68451 F1      0.621 4
 UniProt:Q07440 B2LA1      0.609 2
 UniProt:O43521 BCL2L11  7 0.589 2
 UniProt:Q07813-1 BAX      0.558 7
 UniProt:Q8N6Y0 USBP1      0.556 3
 UniProt:P40855 PEX19  1 0.556 3
 UniProt:Q13064 MKRN3      0.556 3
 UniProt:Q9UHD9 UBQLN2  1 0.556 3
 UniProt:P43364-2 MAGEA11      0.556 3
 UniProt:Q86UW9 DTX2  1 0.556 3
 UniProt:P03495 NS1      0.508 2
 UniProt:Q92934 BAD  4 0.499 2
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