ZC3HAV1(2-624)-p-BRAF(439-766) fusion [cytosol]

Stable Identifier
R-HSA-6802557
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Stransky, N, Cerami, E, Schalm, S, Kim, JL, Lengauer, C

Nat Commun 2014
External Reference Information
External Reference
UniProt:Q7Z2W4 ZC3HAV1
Gene Names
ZC3HAV1, ZC3HDC2, PRO1677
Chain
initiator methionine:1, chain:2-902
Reference Genes
BioGPS Gene:56829 ZC3HAV1
COSMIC (genes):ZC3HAV1 ZC3HAV1
CTD Gene:56829 ZC3HAV1
dbSNP Gene:56829 ZC3HAV1
ENSEMBL:ENSG00000105939 ZC3HAV1
HGNC:23721 ZC3HAV1
KEGG:hsa:56829 ZC3HAV1
Monarch:56829 ZC3HAV1
NCBI Gene:56829 ZC3HAV1
OMIM:607312 ZC3HAV1
UCSC:Q7Z2W4 ZC3HAV1
Reference Transcript
Participates
as a component of
Other forms of this molecule
ZC3HAV1(2-624)-BRAF(439-766) fusion [cytosol]
Modified Residues
Name
Insertion of residues 439 to 766 at 625 from UniProt:P15056 BRAF
Coordinate
625
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 599
Coordinate
599
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 602
Coordinate
602
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
thyroid carcinoma DOID:3963 head and neck cancer, Thyroid
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
ENSEMBL
OpenTargets
Mondo
GeneCards
HPA
PRO
Pharos - Targets
GlyGen
PDB
Interactors (11)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P67809 YBX1  5 0.564 4
 UniProt:Q9NQT4 EXOSC5  3 0.536 2
 UniProt:Q9H9Z2 LIN28A  1 0.527 3
 UniProt:Q15646 OASL  1 0.527 2
 UniProt:P03372 ESR1  10 0.527 3
 UniProt:O95786 RIGI  4 0.524 3
 UniProt:Q12906 ILF3  3 0.483 2
 UniProt:Q9NR30 DDX21  1 0.483 2
 UniProt:P13569 CFTR  17 0.483 8
 UniProt:P62753 RPS6  4 0.483 4
 UniProt:Q8WYQ5 DGCR8  1 0.483 3
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